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Journal of Tea Science ›› 2006, Vol. 26 ›› Issue (2): 122-127.doi: 10.13305/j.cnki.jts.2006.02.009

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Toxicological Research of the Edible Safety of Green Tea Buccal Tablets

SU Mi-ju, WANG Yue-fei*, LUO Yao-ping, LI Liang, YANG Xian-qiang   

  1. Department of Tea Science, Zhejiang University, Hangzhou 310029, China
  • Received:2005-09-15 Revised:2005-09-27 Online:2006-06-25 Published:2019-09-10

Abstract: To evaluate the edible safety of green tea buccal tablets(GTBT), tests included acute toxicity test, Aames test, Micronucleus test, Sperm shape abnormality test and thirty days feeding test were performed. Results shows that: The oral maximum tolerated dose(MTD) was higher than 20.0βg/kg·bw both in male or female mice and rats. Ames test, Micronucleus test and Sperm shape abnormality test were positive. No significant toxicity was detected in thirty days feeding test. Conclusion: Green tea buccal tablets has no acute toxicity, no genotoxicity, high in edible safety.

Key words: green tea buccal tablets, acute toxicity, maximum tolerated dose, genotoxicity, edible safety

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