白茶体外抗氧化与体内抗衰老作用的研究

doi:10.13305/j.cnki.jts.2018.06.008

Abstract

Abstract: To in vitro and in vivo evaluate and compare the antioxidant and anti-aging activities of white tea with different sources of raw materials, Baihaoyinzhen (YZ), Baimudan (MD), Shoumei (SM) were prepared and extracted to measure the main efficacy components. In vitro antioxidant assay, the antioxidantβactivitiesβwereβ also tested. For in vivo anti-aging test, the mice were subcutaneously injected with D-galactose and separately orally administered white tea extracts for aging model analysis. The contents of main efficacy components in YZ extract were higher than those in MD and SM extracts. The contents of tea polyphenols and flavonoids in SM extract were higher than those in MD extract. In vitro, YZ extract had better antioxidant capacity, and there was no obvious difference between SM and MD extract. In vivo, the degree of liver lipid peroxidation in YZH and YZL mice were significantly (P<0.05) decreased. The antioxidant enzyme activities were significantly (P<0.05) increased in serum of SMH and SML mice. But it did not show a dose-dependent manner. The 3 kinds of white tea extracts could up-regulate the expression levels of antioxidant enzymes and anti-aging genes to improve the oxidative stress state and it showed a dose-dependent manner. And there was no hepatotoxicity in these group mice.

Key words: white tea, D-galactose, antioxidant, anti-aging, safety

CLC Number:

TS272.5⁺9

ZENG Qi, REN Fazheng, LEI Xingen, HOU Caiyun. Antioxidant and Anti-aging Activities of White Tea[J]. Journal of Tea Science, 2018, 38(6): 615-624.

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Antioxidant and Anti-aging Activities of White Tea

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