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Journal of Tea Science ›› 2017, Vol. 37 ›› Issue (2): 119-129.

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Progress on the Preparation Technologies and the Active Improvement of EGCG Nano-carriers

QI Jie1, XU Yinglei1, LIANG Wenyi1, FEI Duo1, WU Xiner1, JIN Jianchang2, DU Qizhen1,*, XU Yongquan3, GAO Ying3   

  1. 1. College of Agriculture and Food Science, Zhejiang Agriculture and Forestry University, Lin'an 311300, China;
    2. College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China
    3. Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China
  • Received:2016-08-16 Revised:2016-10-13 Online:2017-04-15 Published:2019-08-22

Abstract: (-)-Epigallocatechin gallate (EGCG) is one of the most important bioactive compounds in green tea, which has shown antitumor activity in various stages of tumor formation. Loading EGCG in nano-carriers is an effective technique to improve the stability and bioavailability of EGCG. Many studies had shown that various kinds of materials can be used for the preparation of nanoparticles as a EGCG nano-carrier, which significantly improved the biological activity of EGCG. The preparation methods, characteristics and the biological activity of EGCG nano-carrier were reviewed, and the improvement of effectiveness by EGCG nanoparticles formulation was also dicussed.

Key words: (-)-Epigallocatechin gallate, nano-carrier, material, preparation, bioavailability

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