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Journal of Tea Science ›› 2016, Vol. 36 ›› Issue (3): 237-244.doi: 10.13305/j.cnki.jts.2016.03.002

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Effect of Pu-erh Tea on Long Chain Fatty Acid Metabolism and Expression of Tight Junction Proteins in the Rat Model of Non-alcoholic Fatty Liver Disease

ZHU Shengyi1, TONG Yuling1, ZHAO Yi1, LÜ Haipeng2, LIN Zhi2, SHEN Guoli1, SUN Ting1, SONG Zhenya1,*   

  1. 1. The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China;
    2. Key Laboratory of Tea Biology and Resource Utilization of Ministry of Agriculture, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China
  • Received:2015-12-21 Online:2016-06-15 Published:2019-08-23

Abstract: In this study, the influence of Pu-erh tea on the absorption of long chain fatty acids in non-alcoholic fatty liver disease (NAFLD) rats was analyzed. Moreover, the possible interventional mechanism was also discussed. Thirty-six SD rats were randomly divided into three groups, normal group (NG), NAFLD group, and Pu-erh tea group (PTG), 12 rats for each group. All rats were killed after 8 weeks. Rat weight, liver index, serum lipid level, intestinal lipid absorption protein (CD36), tight junction proteins (Occludin, ZO-1), and TNF-α mRNA were measured.

Key words: Pu-erh tea, nonalcoholic fatty liver disease (NAFLD), lipid metabolism, tight junction

CLC Number: