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Journal of Tea Science ›› 2015, Vol. 35 ›› Issue (5): 458-464.doi: 10.13305/j.cnki.jts.2015.05.008

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Review on the Effect of Tea on Platelet Activation

CHEN Ping, QIU Pei, CHENG Hao, ZHOU Ying, GONG Shuying*   

  1. Department of Tea Science, Zhejiang University, Hangzhou 310058, China
  • Received:2015-05-11 Revised:2015-07-16 Online:2015-10-15 Published:2019-08-26

Abstract: Platelet activation is the basis of the incidence of many cardiovascular disease, antiplatelet drugs could block the cascade of platelet aggregation in different levels. As confirmed by clinical research and animal experiments, tea and tea ingredients can inhibit platelet aggregation. Catechins exhibit a structure-activity relationship in antiplatelet effect. This review summarized recent progress in the effect of tea and tea ingredients on platelet activity or platelet aggregation in vitro, in vivo and ex vivo, and also the effect on thrombus and coagulation system. The mechanism of anti-aggregatory effect of tea is explored, which provide further confirmation for its antithrombotic function and the preventive effect for cardiovascular disease.

Key words: tea ingredients, platelet activation, platelet aggregation, antithrombotic

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