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茶叶科学 ›› 2003, Vol. 23 ›› Issue (2): 83-93.doi: 10.13305/j.cnki.jts.2003.02.001

• •    下一篇

茶多酚类化合物抗癌的生物化学和分子生物学基础

陈宗懋   

  1. 中国农业科学院叶研究所, 浙江 杭州 310008
  • 出版日期:2003-11-25 发布日期:2019-09-16
  • 作者简介:陈宗懋(1933- ),男,浙江海盐人,研究员,博士生导师,主要从事茶树植保和农药残留研究。

Biochemical and Molecular Biological Basis on The Anticarcinogenic Activity of Tea Polyphenolic Compounds

CHEN Zong-mao   

  1. Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, Chin
  • Online:2003-11-25 Published:2019-09-16

摘要: 本文对近五年来国际上关于茶多酚类化合物对人体抗癌活性及其机理的研究进展进行了分析和综述。全文分抗氧化活性、对关键酶的调控、阻断信息传递、抗血管形成和细胞凋亡五个方面讨论了其抗癌机理,并对茶多酚今后的开发前景和研究动向进行了讨论。

关键词: 茶学, 生物化学, 分子生物学, 茶多酚, 抗癌机理

Abstract: The progress in the investigation of anticarcinogenic activity of tea polyphenols and its biochemical and molecular biological mechanisms in the world in recent 5 years were analyzed and reviewed in this paper. The mechanism of anticarcinogenic activity was discussed from the following 5 aspects: antioxidative activity, modulation on the key enzymes, blockage of signal transduction, antiangiogenic activity and the apotopsis of cancer cells. The developmental prospect and the investigational tendency of tea polyphenols in the future were discussed.

Key words: Tea science, Biochemistry, Molecular biology, Tea polyphenols, Anticarcinogenic mechanism

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