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茶叶科学 ›› 2016, Vol. 36 ›› Issue (4): 354-362.doi: 10.13305/j.cnki.jts.2016.04.003

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绿茶茶汤对肥胖相关肠道菌群的影响

郭虹雯, 许翔雨, 陈莹婕, 倪莉, 刘志彬*   

  1. 福州大学食品科学技术研究所,福建省食品生物技术创新技术研究中心,福建 福州 350108
  • 收稿日期:2016-04-01 出版日期:2016-08-15 发布日期:2019-08-26
  • 通讯作者: *,liuzhibin@fzu.edu.cn
  • 作者简介:郭虹雯,女,硕士研究生,主要从事茶叶生理功能方面的研究。
  • 基金资助:
    国家自然科学基金资助(31501494)

Effect of Green Tea Infusions on Obesity-associated Gut Microbiota

GUO Hongwen, XU Xiangyu, CHEN Yingjie, NI Li, LIU Zhibin*   

  1. Institute of Food Science and Technology, Fuzhou University, Fujian Center of Excellence for Food Biotechnology, Fuzhou 350108, China
  • Received:2016-04-01 Online:2016-08-15 Published:2019-08-26

摘要: 近年来,饮茶调节肠道微生态的效果受到广泛关注。本研究通过将绿茶茶汤与志愿者新鲜粪样混合培养,使用荧光原位杂交技术考察不同发酵时间点(0、6、12、24 h)绿茶茶汤对与肥胖密切相关的肠道菌群(包括总菌、拟杆菌门微生物和厚壁菌门微生物)的影响,从而评估绿茶茶汤调节肠道微生态作用的效果。实验结果表明,绿茶茶汤在体外粪样混合培养体系中发酵24 h时,对于肠道中总菌、拟杆菌门微生物以及厚壁菌门微生物的数量减少有抑制效果(P<0.05),并可以改善肠道中拟杆菌门与厚壁菌门的相对丰度,降低厚壁菌门与拟杆菌门比例(F/B),这为饮茶对改善肠道健康、减肥降脂作用提供了一定的理论参考。

关键词: 绿茶茶汤, 肠道菌群, 肥胖, 拟杆菌门微生物, 厚壁菌门微生物

Abstract: In recent years, the effect of tea on intestinal microflora attracted widespread attention. In this study, the green tea infusion with human fecal was mixed, the change of intestinal flora related to obesity in different fermentation time points (0, 6, 12, 24 h) were measured and the role of tea regulated intestinal microflora was evaluated. The results showed that green tea infusion inhibited the reduction of total gut bacteria, Bacteroides and Firmicutes after fermentation for 24 h (P<0.05), improved the relative abundance of Bacteroides and Firmicutes, reduced the F/B ratio, which provides a reference to support the important role of green tea infusion in improving intestinal health, reducing weight and lowering blood lipid.

Key words: green tea infusion, intestinal bacteria, obesity, Bacteroides, Firmicutes

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