A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM2.5

LIU Jianjun; LI Meifeng; ZHANG Jing; TIAN Lili; DENG Yanli; LIN Haiyan; HUANG Jian&#x02032;an; LIU Zhonghua

doi:10.13305/j.cnki.jts.2021.04.006

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Journal of Tea Science ›› 2021, Vol. 41 ›› Issue (4) : 525-534. DOI: 10.13305/j.cnki.jts.2021.04.006

Research Paper

A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM_2.5

LIU Jianjun^1,2,3, LI Meifeng³, ZHANG Jing^1,2,3, TIAN Lili^1,2,4, DENG Yanli^1,2,3, LIN Haiyan^1,2, HUANG Jian′an^1,2,*, LIU Zhonghua^1,2,*

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Abstract

In this study, the healthy male sprague-dawley (SD) rats were taken as experimental subjects, and the water extracts of Xinyang Maojian tea were used as test substances, while intratracheal instillation of PM_2.5 suspension was established as chronic pulmonary injury model. Rats serum and biochemical indexes of bronchoalveolar lavage fluid (BALF) were tested. The results show that the tea extracts had antagonism effects on the reduce of rats growth rate and the lung injury caused by PM_2.5. Furthermore, the tea water extracts could effectively lower the increase of IL-1β, IL-6, TNF-α, IgG and the activity of LDH, and keep the activity of SOD in rats serum and BALF, showing a dose-dependent effects.

Key words

alleviate / fine particulate matter / intratracheal instillation / pulmonary injury / Xinyang Maojian tea

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LIU Jianjun, LI Meifeng, ZHANG Jing, TIAN Lili, DENG Yanli, LIN Haiyan, HUANG Jian′an, LIU Zhonghua. A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM_2.5[J]. Journal of Tea Science. 2021, 41(4): 525-534 https://doi.org/10.13305/j.cnki.jts.2021.04.006

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