欢迎访问《茶叶科学》,今天是

茶叶科学 ›› 2008, Vol. 28 ›› Issue (2): 107-110.doi: 10.13305/j.cnki.jts.2008.02.012

• • 上一篇    下一篇

乌龙药茶对高脂血症大鼠血脂水平的调节和血管内皮保护作用的研究

郑良朴, 林薇, 叶蕻芝, 陈文列, 胡海霞   

  1. 福建中医学院福建省高校中西医结合基础重点实验室,福建中西医结合研究院,福建 福州,350108
  • 收稿日期:2007-10-08 修回日期:2008-01-11 出版日期:2008-04-15 发布日期:2019-09-16
  • 作者简介:郑良朴(1974— ),男,福建福州人,实验师,主要研究方向为中西医结合基础。Tel: 0591-22861168
  • 基金资助:
    安溪铁观音集团研发基金

The Regulation of Oolong Herb Tea on the Serum Lipid Level and the Preventive Effects of ECV in Experimental Hyperlipidemia Rats

ZHENG Liang-pu, LIN Wei, YE Hong-zhi, CHEN Wen-lie, HU Hai-xia   

  1. Fujian College of TCM State Key Laboratory of Basics of Integrative Medicine, Fujian Province University,Fujian Academy of Integrative Medicine,Fuzhou 350108, China
  • Received:2007-10-08 Revised:2008-01-11 Online:2008-04-15 Published:2019-09-16

摘要: 采用高脂饲料饲喂法建立高脂血症大鼠模型,通过药、茶和乌龙药茶分别灌胃,实验35 d后,检测大鼠血液丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆固醇(TCHO)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、一氧化氮(NO)和内皮素-1(ET-1)的含量,以及观察大鼠的一般情况和肝、肾组织的病理变化,来观察乌龙药茶对实验性高脂血症大鼠血脂水平调节和血管内皮细胞的保护作用。结果表明,药、茶和乌龙药茶均能明显降低模型大鼠血液TCHO、TC、LDL-C和ET-1含量,提高HDL-C和NO含量(P<0.05,P<0.01),其中,乌龙药茶作用显著优于药、茶。研究结论,药、茶和乌龙药茶均能显著调节机体的血脂水平,有效预防高脂血症和保护血管内皮细胞功能;乌龙药茶表现为药与茶两者协同作用、提高功效。

关键词: 乌龙药茶, 高脂血症, 大鼠

Abstract: To establish the hyperlipidmia rat models by feeding high lipid diet, then the herb, tea and oolong herb tea were irrigated into stomach separately for 35 days in succession, the level on the activity of ALT, AST enzyme and the level of cholesterols of TCHO, TG, HDL-C, LDL-C, as well the contents of NO and ET-1 in rat blood measured were measured. Meanwhile, the general conditions and histopathological changes in tissues of liver and kidney were observed to explore the influence of Oolong herb tea on the serum lipid level and the preventive effect on vein endothelium cells in experimental hyperlipidemia rats investigated. Results showed that compared the blood levels of TCHO, TC, LDL-C, TCHO and the ET-1 content were reduced significantly in treatment group while HDL-C and NO increased(P<0.05, P<0.01) compared with the control group. The effect of Oolong herb tea was more remarkable than that of herb and tea treatment. It is concluded that the herb, tea and Oolong herb tea are able to regulate the level of serum lipid effectively prevent hyperlipidemia and have a protective effect of vein endothelium cells. It is showed that the synergistic effect between herb and tea and improve the efficacy in Oolong herb tea.

Key words: Oolong herbs tea, hyperlipidemia, rat

中图分类号: