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茶叶科学 ›› 2009, Vol. 29 ›› Issue (3): 196-199.doi: 10.13305/j.cnki.jts.2009.3.003

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乌龙药茶对高脂血症大鼠血脂代谢、尿酸代谢的影响

林薇, 郑良朴, 叶蕻芝, 陈文列*   

  1. 福建中医学院福建省高校中西医结合基础重点实验室,福建中西医结合研究院,福建 福州 350108
  • 收稿日期:2008-10-06 修回日期:2008-11-27 出版日期:2009-06-15 发布日期:2019-09-06
  • 通讯作者: * chen.wl@163.com
  • 作者简介:林薇(1974— ),女,助理研究员,主要研究方向为中西医结合基础。
  • 基金资助:
    安溪铁观音集团研发基金

Effects of Oolong Herb Tea on Blood Lipids and Uric Acid Metabolism in Experimental Hyperlipidemia Rat

LIN Wei, ZHENG Liang-pu, YE Hong-zhi, CHEN Wen-lie*   

  1. Fujian College of TCM State Key Lab of Basics of Integrative Medicine, Fujian Province University, Fujian Academy of Integrative Medicine, Fuzhou 350108, China
  • Received:2008-10-06 Revised:2008-11-27 Online:2009-06-15 Published:2019-09-06

摘要: 观察乌龙药茶对高脂血症大鼠血脂水平、尿酸水平调节,以及对肝组织的影响。采用高脂并酒精喂养大鼠建立高脂血症模型,通过药、茶和乌龙药茶分别灌胃,观察大鼠的一般情况及肝、肾组织的病理变化,检测大鼠丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆固醇(TCHO)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸(UA)、黄嘌呤氧化酶(XOD)的含量。结果为药、茶和乌龙药茶均能显著降低模型大鼠血液ALT、AST、UA、TCHO、TC、LDL-C、UA、XOD含量,提高HDL-C含量(P<0.05,P<0.01),其中,乌龙药茶作用显著优于药、茶。研究结论,药、茶和乌龙药茶均能显著调节机体的血脂水平和尿酸水平,乌龙药茶表现为药与茶两者协同作用,提示乌龙药茶对高脂血症具有一定的预防保健作用。

关键词: 乌龙药茶, 高脂血症, 大鼠

Abstract: The effects of oolong herb tea on the serum lipid level and uric level and the influence of liver tissue in Expermental Hyperlipidemia Rats were investigated. To establish the hyperlipidmia rat model by feeding of high lipid diet and ethanol, as well as feed the herb, tea and oolong herb tea by intragastic for 35 days, measure the level of ALT, AST, TCHO, TG, HDL-C, LDL-C, as well as the contents of UA and XOD in rat blood. The general conditions and histopathological changes in tissues of liver and kidney were observed. Results showed that the herb, tea and oolong herb tea could reduce significantly the TCHO, TC, LDL-C, TCHO, UA and XOD and increase the HDL-C level (P<0.05, P<0.01). The effect of oolong herb tea was more remarkable than that of herb and tea treatment. It is concluded that the herb, tea and oolong herb tea are able to regulate the level of serum lipid and uric acid effectively, and showed a protective effect of vein endothelium cells. It is showed that the synergistic effect between herb and tea and improve the efficacy in oolong herb tea.

Key words: oolong herbs tea, hyperlipidemia, rat

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