绿茶EGCG防癌作用的分子靶点

顾成波; 袁肖寒; 付玉杰; 祖元刚; 赵恩泽; 李旺; 王秋雪

doi:10.13305/j.cnki.jts.2010.06.002

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茶叶科学 ›› 2010, Vol. 30 ›› Issue (6) : 414-422. DOI: 10.13305/j.cnki.jts.2010.06.002

绿茶EGCG防癌作用的分子靶点

顾成波^1,2,5, 袁肖寒^3,4, 付玉杰^1,2, 祖元刚^1,2,*, 赵恩泽^1,2, 李旺^1,2, 王秋雪^1,2

作者信息 +

Molecular Targets for Cancer Chemoprevention by (-)-Epigallocatechin Gallate of Green Tea

GU Cheng-bo^1,2,5, YUAN Xiao-han^3,4, FU Yu-jie^1,2, ZU Yuan-gang^1,2,*, ZHAO En-ze^1,2, LI Wang^1,2, WANG Qiu-xue^1,2

Author information +

文章历史 +

摘要

表没食子儿茶素没食子酸酯（EGCG）是绿茶中含量最高、活性最强的多酚类成分。近年来绿茶EGCG癌症预防作用的分子靶点一直备受关注。本文对已报道的EGCG癌症预防作用机制及其可能的作用靶点进行了综述,讨论了将EGCG开发为癌症化学预防剂应采取的策略,以期为设计预防癌症的新方案提供借鉴。

Abstract

(-)-Epigallocatechin gallate (EGCG) is the most active and major polyphenolic compound in green tea. The molecular mechanisms and targets on the action of EGCG have been extensively investigated. This paper reviewed some of the reported mechanisms and possible targets for the action of EGCG, and strategies for cancer chemoprevention by EGCG in clinical trials were discussed. It provides a new inspiration for cancer chemoprevention.

导出引用

顾成波, 袁肖寒, 付玉杰, 祖元刚, 赵恩泽, 李旺, 王秋雪. 绿茶EGCG防癌作用的分子靶点[J]. 茶叶科学. 2010, 30(6): 414-422 https://doi.org/10.13305/j.cnki.jts.2010.06.002

GU Cheng-bo, YUAN Xiao-han, FU Yu-jie, ZU Yuan-gang, ZHAO En-ze, LI Wang, WANG Qiu-xue. Molecular Targets for Cancer Chemoprevention by (-)-Epigallocatechin Gallate of Green Tea[J]. Journal of Tea Science. 2010, 30(6): 414-422 https://doi.org/10.13305/j.cnki.jts.2010.06.002

中图分类号： TS272 R730.1

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