茶多酚保健功能研究进展与保健食品开发

邬新荣; 王岳飞; 张士康; 徐平; 杨贤强

PDF(182 KB)

茶叶科学 ›› 2010, Vol. 30 ›› Issue (S1) : 501-505.

茶多酚保健功能研究进展与保健食品开发

邬新荣¹, 王岳飞^2,*, 张士康³, 徐平², 杨贤强²

作者信息 +

Research Progress on the Health Functions of Tea Polyphenols and Development of Healthy Foods

WU Xin-rong¹, WANG Yue-fei^2,*, ZHANG Shi-kang³, XU Ping², YANG Xian-qiang²

Author information +

文章历史 +

摘要

作为一类出色的天然抗氧化剂,茶多酚的保健功能研究一直是国内外研究的热点之一。本文介绍了近年来流行病学研究和临床研究在茶多酚对癌症、心血管疾病、神经退行性疾病、皮肤疾病等多种疾病的防治功能的最新发现。同时,简单分析了我国利用茶多酚开发保健食品的现状,并从进一步发挥茶多酚保健功能的角度对茶多酚保健食品开发进行了的展望。

Abstract

As a great natural antioxidant, tea polyphenols (TP) and its health function has been one of hot-topic studies at home and abroad. This paper reviewed the new outcomes of epidemiological and clinical studies on tea and health, which including prevention and treatment of cancers, cardiovascular diseases, neurodegenerative diseases and other diseases by TP. Meanwhile the current development and prospects on healthy foods of TP were also mentioned.

导出引用

邬新荣, 王岳飞, 张士康, 徐平, 杨贤强. 茶多酚保健功能研究进展与保健食品开发[J]. 茶叶科学. 2010, 30(S1): 501-505

WU Xin-rong, WANG Yue-fei, ZHANG Shi-kang, XU Ping, YANG Xian-qiang. Research Progress on the Health Functions of Tea Polyphenols and Development of Healthy Foods[J]. Journal of Tea Science. 2010, 30(S1): 501-505

中图分类号： TS272 TS218

参考文献

[1] 杨贤强, 王岳飞, 陈留记. 茶多酚化学[M]. 上海: 上海科学技术出版社, 2003.
[2] McLarty J, Bigelow RL, Smith M, et al. Tea polyphenols decrease serum levels of prostate-specific antigen, hepatocyte growth factor, and vascular endothelial growth factor in prostate cancer patients and inhibit production of hepatocyte growth factor and vascular endothelial growth factor in vitro[J]. Cancer Prev Res (Phila Pa), 2009, 2(7): 673-682.
[3] Prostate Cancer Clinical Trials on the web: Clinical Trials. gov identifier: NCT00459407.
[4] Clinical Trials on the web: CASE13805. http://henge.case.edu/sip/SIPControlServlet.
[5] Yang Y C, Lu F H, Wu J S, et al. The protective effect of habitual tea consumption on hypertension[J]. Archives of Internal Medicine, 2004, 164(14): 1534-1540.
[6] Nagao T, Hase T, Tokimitsu I.A green tea extract high in catechins reduces body fat and cardiovascular risks in humans[J]. Obesity (Silver Spring), 2007, 15(6): 1473-1483.
[7] Davies M J, Judd J T, Baer D J, et al. Black tea consumption reduces total and LDL cholesterol in mildly hypercholesterolemic adults[J]. Journal of Nutrition, 2007, 133(10): 3298S-3302S.
[8] 龚金炎, 焦梅, 吴晓琴, 等. 茶叶减肥作用的研究进展[J]. 茶叶科学, 2007, 27(3): 179-184.
[9] Matsuyama T, Tanaka Y, Kamimaki I, et al. Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children[J]. Obesity (Silver Spring), 2008, 16(6): 1338-1348.
[10] Pan T, Jankovic J, Le W.Potential therapeutic properties of green tea polyphenols in Parkinson's disease[J]. Drugs Aging, 2003, 20(10): 711-721.
[11] Mandel S A, Amit T, Kalfon L, et al. Targeting multiple neurodegenerative diseases etiologies with multimodal-acting green tea catechins[J]. J Nutr, 2008, 138(8):1578S-1583S.
[12] Guo S, Yan J, Yang T, et al. Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway[J]. Biol Psychiatry, 2007, 62(12): 1353-1362.
[13] Mandel S A, Amit T, Weinreb O, et al. Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases[J]. CNS Neurosci Ther, 2008, 14(4): 352-365.
[14] Yamada H, Takuma N, Daimon T, et al. Gargling with tea catechin extracts for the prevention of influenza infection in elderly nursing home residents: a prospective clinical study[J]. J Altern Complement Med, 2006, 12(7): 669-672.
[15] Hsu S, Bollag W B, Lewis J, et al.Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes[J]. Journal of Pharmacology and Experimental Therapeutics, 2003, 306(1):29-34.
[16] Janjua R, Munoz C, Gorell E, et al. A two-year, double-blind, randomized placebo-controlled trial of oral green tea polyphenols on the long-term clinical and histologic appearance of photoaging skin[J]. Dermatol Surg, 2009, 35(7): 1057-1065.
[17] Bukowski J F, Percival S S.L-theanine intervention enhances human gammadeltaT lymphocyte function[J]. Nutr Rev, 2008, 66(2): 96-102.
[18] Kim H R, Rajaiah R, Wu Q L, et al. Green tea protects rats against autoimmune arthritis by modulating disease-related immune events[J]. J Nutr, 2008, 138(11): 2111-2116.