利用链脲佐菌素（STZ）复制糖尿病大鼠模型,研究乌龙茶多糖对糖尿病大鼠肝肾抗氧化功能和组织形态变化的影响。结果表明,糖尿病大鼠灌胃乌龙茶多糖4周后,肝肾SOD和GSH-PX活性明显提高,MDA含量显著下降,抗氧化能力增强;茶多糖对糖尿病大鼠肝肾组织有保护作用。
The influence of polysaccharide extracted from Oolong tea（OTPS） on hepatic-nephritic anti oxidation and histomorphology in mice with streptozotocin (STZ)-induced diabetes(MD) was investigated. Results showed that SOD and GSH-PX activity was increased and MDA content decreased in liver and kidney of MD mice fed OTPS for 4 weeks. OTPS had the function of improving the antioxidation and protecting the liver and kidney of MD mice.
[1] 汪东风,谢晓风. 茶叶多糖及其药理作用研究进展[J]. 天然产物研究与开发,1996,8(1):63~67.
[2] 李布青,张惠玲. 中抵挡绿茶中茶多糖的提取及降血糖作用[J]. 茶叶科学,1996,16(1):67~72.
[3] 陈海霞,谢笔钧. 茶多糖对小鼠实验性糖尿病的防治作用[J]. 营养学报,2002,24(1):85~86.
[4] 倪德江,宋春和,谢笔钧. 不同茶类多糖降血糖效果的比较研究[J]. 茶叶科学,2002,2.
[5] 邹如政. 糖尿病从肝论治[J]. 中国医药学报,1998,V13(1):17~23.
[6] 韦敏怡. 糖尿病性肝病的研究进展[J]. 广西医科大学学报,1996,13(1):112~115.
[7] 仝小林,段军,周水平.糖尿病肾病中西医诊治中的几个问题[J]. 中国医药学报,2002,V17(5):300~303.
[8] 王淑英,王建业. 自由基在糖尿病中的致病作用[J]. 洛阳医专学报,1995,14(3):183~185.
[9] 赵明,王亦根,张雯,等. 超氧化物歧化酶对STZ诱发糖尿病自由基代谢的影响[J]. 中国糖尿病杂志,1995,V3(1):44~46.
[10] T San, F Umeda, T Hashimoto et al. Dative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes[J]. Diabetologia, 1998, 41(11): 1355~1360.
[11] M.Damico, R Marfella, F Nappo et al. Igh glucose induces ventricular instability and increases vasomotor tone in rats[J]. Diabetologia, 2001, 44(4): 464~470.
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