Green tea polysaccharides was modified by using glycosidase extracted from tea, the effect of enzymatic modification of green tea polysaccharides on immune function of the immunosuppressant mice inhibited by cyclophosphamide was studied. The results showed that, TPS and ETPS were positive in the cell immune function, humor immune function, mononuclear macrophage function and NK cell activity tests. So it can be concluded that they could obviously improve both the cell immune function and humor immune function in immunosuppressant mice. The results also made clear that the enzymatic modification could significantly enhance the immune activity of green tea polysaccharides. With the same dose, ETPS could improve the spleen index, the phagocytosis rate and index of peritoneal macrophage, the level of ear swell in DTH, HC50 in serum and NK cell activity compared with the original TPS. Collectively, these data proved that the immune activity of green tea polysaccharides after enzymatic modification was significantly improved.
Key words
enzymatic modification /
green tea /
immunocompetence /
tea polysaccharide
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