酶法修饰绿茶多糖对免疫低下模型小鼠免疫活性的影响

Abstract

Abstract: Green tea polysaccharides was modified by using glycosidase extracted from tea, the effect of enzymatic modification of green tea polysaccharides on immune function of the immunosuppressant mice inhibited by cyclophosphamide was studied. The results showed that, TPS and ETPS were positive in the cell immune function, humor immune function, mononuclear macrophage function and NK cell activity tests. So it can be concluded that they could obviously improve both the cell immune function and humor immune function in immunosuppressant mice. The results also made clear that the enzymatic modification could significantly enhance the immune activity of green tea polysaccharides. With the same dose, ETPS could improve the spleen index, the phagocytosis rate and index of peritoneal macrophage, the level of ear swell in DTH, HC50 in serum and NK cell activity compared with the original TPS. Collectively, these data proved that the immune activity of green tea polysaccharides after enzymatic modification was significantly improved.

Key words: green tea, tea polysaccharide, enzymatic modification, immunocompetence

CLC Number:

TS272
R285.5

YU Zhi, SHI Yu-tao, NI De-jiang. Effect of Enzymatic Modification Green Tea Polysaccharide on Immune Function of the Immunosuppressant Mice[J]. Journal of Tea Science, 2010, 30(S1): 567-572.

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Effect of Enzymatic Modification Green Tea Polysaccharide on Immune Function of the Immunosuppressant Mice

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