The smoke chemical constituents from blended tobacco cigarette to which reconstituted tobacco containing different proportion of tea dust were added and smoked by smoking machine, extracted through the simultaneous and extraction method (SDE), and then investigated by gas chromatography-mass spectrometry (GC-MS). Compared with the blank control sample, it showed that the flavor components in blended tobacco containing different proportion of tea dust were increased in different degrees: the total contents of carboxylic acids, heterocyclics, carbonyls, esters and alcohols increase 175.08%, 58.46%, 48.57%, 40.83% and 16.47% respectively on average, and the contents of heterocyclics, esters, carboxylicacids and carbonyls were increased as the increasing of the adding proportion of tea dust. The 13 main harmful components were detected totally and the total contents were decreased 19.0%, 40.7%, 10.6% and 17.1% in the samples that added 10%, 12%, 14% and 16% of tea dust respectively.