100 volunteers were employed in this study and divided into two groups randomly with 50 subjects in each group, i.e., treatment and control groups. People in the treatment group administrated TCP orally 2 times per day and 3 capsules per time. TCP was found to be effective in 28 cases, with a total effective rate of 56%. After a 30-day period, the color and area of chloasma decreased significantly as compared with those examined before TCP administration and control group, which indicted that TCP had the function of dispelling chloasma,and no obviously adverse influence on tested persons.
WANG Yue-fei
,
SU Mi-ju
,
TONG Lin
,
YANG Xian-qiang
. Effects of Tea Catechins Preparation (TCP) on Chloasma[J]. Journal of Tea Science, 2005
, 25(2)
: 90
-94
.
DOI: 10.13305/j.cnki.jts.2005.02.002
[1] 郑建仙. 功能性食品学[M]. 北京: 中国轻工业出版社, 2003, 1: 175.
[2] 凌关庭. 保健食品原料手册[M]. 北京: 化学工业出版社, 2004, 1: 600~618.
[3] 杨贤强, 王岳飞, 陈留记. 茶多酚化学[M]. 上海: 上海科学技术出版社, 2003, 12: 345~371.
[4] 胡秀芳, 沈生荣, 朴宰日, 等. 茶多酚抗氧化机理研究现状[J]. 茶叶科学, 1999, 19(2): 93~103.
[5] 保健食品检验与评价技术规范. 中华人民共和国卫生部, 北京, 2003.
[6] 林新瑜. 黄褐斑的病因及治疗[J]. 中国皮肤性病学杂志, 1999, 13(5): 301~302.
[7] 戴伟, 李立. 芦荟制品祛黄褐斑作用的人体试食观察研究[J]. 环境与职业医学, 2003, 20(3): 230~232.
[8] 张静, 张其, 文海泉, 等. 儿茶素治疗黄褐斑疗效观察及机理初探[J]. 中华医学美容杂志. 1998, 4(4):176~178
[9] Yoshida, Yuko, et al. Efficiency of the extraction of catechins from green tea[J]. Food Chemistry 1999, 67(4): 429~433
[10] 黄华涛, 许心青. 茶抗癌活性的动物试验和人体研究新进展(英文)[J]. 茶叶科学, 2004, 24(1): 1~11
[11] Maeda, Keiko, et al. Green tea catechins inhibit the cultured smooth muscle cell invasion through the basement barrier[J]. Atherosclerosis, 2003, 166(1): 23~30.
[12] 朱永兴, 邓君奇. 中国茶医学科技文献研究[J]. 茶叶科学, 2003, 23(2): 129~135.
[13] 陈瑗, 周玫. 自由基医学基础与病理生理[M]. 北京: 人民卫生出版社, 2002.
浙公网安备 33019902000101号 
