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Study on the Hypoglycemic Mechanism of Tea Polysaccharides and Tea Polyphenols

  • DING Ren-feng ,
  • HE Pu-ming ,
  • JIE Guo-liang
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  • Department of Tea Science, Zhejiang University, Hangzhou 310029, China

Online published: 2019-09-16

Abstract

The investigation on the hypoglycemic mechanism of tea polysaccharides and tea polyphenol in diabetic SD rats induced by alloxan was conducted. Methods: After feeding tea polysaccharides or polyphenols for 3 weeks, the changes of the level of blood glucose, insulin and the activities of amylase, sucrase and maltase in small intestine were inspected in diabetic rats. Results about that the suppressive effect of high level of blood glucose induced by alloxan was observed in the groups feeded with tea polysaccharides or tea polyphenols obviously in the experimental period. Compared with control group, the level of blood insulin in the group feeded with tea polysaccharides was increased significantly (P<0.05), the activity of sucrase and maltase were decreased significantly. Almost the same change without significance was observed in the group feeded with tea polyphenols while compared with the control group. Investigation indicated that the tea polysaccharides and tea polyphenols have remarkable suppressive hyperglycemic effect on diabetic rats induced by alloxan. These results suggested that functionary mechanisms of the suppressive hyperglycemic effect of tea polysaccharides may be induced by controlling the activities of sucrase and maltase.

Cite this article

DING Ren-feng , HE Pu-ming , JIE Guo-liang . Study on the Hypoglycemic Mechanism of Tea Polysaccharides and Tea Polyphenols[J]. Journal of Tea Science, 2005 , 25(3) : 219 -224 . DOI: 10.13305/j.cnki.jts.2005.03.011

References

[1] 刘强. 茶的保健功能与药用便方[M]. 北京: 金盾出版社, 1990: 31.
[2] 安徽农业大学. 茶叶生物化学(第二版)[M], 北京农业出版社, 1988: 293.
[3] 汪东风, 谢晓凤. 粗老茶治糖尿病的药理成分分析[J]. 中草药, 1995, 26(5): 255~257.
[4] 汤圣兴, 陈月平. 茶多酚对链脲佐链菌素诱发糖尿病大鼠降糖作用的实验研究[J]. 中药药理与临床, 2001, 17(3): 17~19.
[5] 李清钊. 茶多酚对糖尿病大鼠的保护作用[J]. 环境与职业医学, 2003, 20(3): 233~235.
[6] 丁仁凤, 何普明. 茶叶与糖尿病关系的研究概况[J]. 茶叶, 2004, 30(4): 207~209.
[7] Sabu M.C, Smitha K. Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stress in experimental diabetes. [J]. Ethnopharmacol, 2002, 83: 109~116.
[8] 汪东风, 谢晓凤. 粗老茶治糖尿病的药理成分分析[J]. 中草药, 1995, 26(5): 255~257.
[9] Isigaki K.Anti-diabetes mellitus effect of water-soluble tea polysaccharide Proceedings of the International Symposium on Tea[J]. Science, August 26~29 1991, Shizuoka, Japan.1991: 240~242.
[10] 曹建明, 谢作叙, 周铁丽. 改良的淀粉酶测定法[J]. 陕西医学检验, 2001, 16(3): 63.
[11] 许梓荣, 李卫芬, 孙建义. 猪胃肠道黏膜二糖酶的性质[J]. 动物学报, 2002, 48(2): 202~207.
[12] 刘星, 陈大为. 福林-酚法测定蜂毒口服结肠定位释药微丸含量[J]. 沈阳药科大学学报, 2003, 20(1): 17~18, 69.
[13] 吴建芬, 冯磊, 张春飞, 等. 茶多糖降血糖机制研究[J]. 浙江预防医学, 2003, 15(9): 9~13.
[14] 陈月平. 茶多酚对链脲佐链菌素糖尿病大鼠的降血糖作用[J]. 皖南医学院学报, 2003, 22(3): 161~162
[15] 刘洪玲, 姜惠卿. 黄芪多糖治疗糖尿病的药理作用探要[J]. 中国药师, 2004(8): 585~587.
[16] 朱永兴, Hervé Huang.茶与健康[M]. 中国农业科学技术出版社, 2004, 162.
[17] N MATSUMOTO, F TONO-OKA.Reduction of blood glucose level by tea catechins[A]. The Organizing Committee of interational symposium on Tea Science(ISTS), 1992: 318.
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