茶氨酸是茶叶特有的化学成分之一,对茶叶品质有重要影响。近年的研究发现茶氨酸有多种保健作用,非常具有开发前景。本文就茶氨酸的性质、生理作用、合成等进行综述。
关键词：
茶学; 茶; 茶氨酸; 生理作用; 合成
The recent researches have found that theanine, an unique and important component in tea plants, has many bioactivities, and made it get more and more attention. The property, bioactivities, and industrial preparation of theanine are reviewed.
[1] Juneja L R, Chu D-C, et al. L-theanine-a unique amino acid of green tea and its relaxation effect in humans. Trends in Food Science & Technology, 1999, 10: 199-204.
[2] 杨贤强. 茶树氮素代谢研究, 茶叶, 1982, 1: 10-16.
[3] 村松敬一郎编. 茶の科学, 东京: 朝仓书店, 1991: 33-36.
[4] Kitaoka S, Hayashi H, et al. Transmural potential changes associated with the in vitro absorption of theanine in the guinea pig intestine. Biosci. Biotech. Biochem., 1996, 60(11):1768-1771.
[5] Terashima T, Takido J, Yokogoshi H.Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. Biosci. Biotech. Biochem., 1999, 63(4): 615-618.
[6] Unno T, Suzuki Y, et al. Metabolism of theanine,γ-glutamylethylamide, in rats. [J]. Agric. Food Chem., 1999, 47(4): 1593-1596.
[7] Yokogoshi H, Kobayashi M, et al. Effect of theanine, γ-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem. Res., 1998, 23(5): 667-673.
[8] Kakuda T, Nozawa A, et al. Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat. Biosci. Biotech. Biochem., 2000, 64(2): 287-293.
[9] 大久保勉. 茶の機能, 村松敬一郎等编, 东京: 学会出版センター, 2002: 318-322.
[10] Juneja L R, 大久保勉. 绿茶テアニンの驚くべき効果. RYOKUCHA, 2002, 1: 29-31.
[11] Kakuda T, Yanase H,et al. Protective effect of γ-glutamylethylamide (theanine) on ischemic delayed neuronal death in gerbils. Neurosci. Lett., 2000, 289(3): 189-192.
[12] Yokogoshi H, Kato Y, et al. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci. Biotech. Biochem., 1995, 59(4): 615-618.
[13] Yokogoshi H,Mochizuki M, Saitoh K.Theanine-induced reduction of brain serotonin concentration in rats. Biosci. Biotech. Biochem., 1998, 62(4): 816-817.
[14] Sadzuda Y, Sugiyama T, et al. The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin. Cancer Lett., 1996,105(2):203-9.
[15] Sugiyama T, Sadzuka Y.Enhancing effects of green tea components on the antitumor activity of adriamycin against M5076 ovarian sarcoma. Cancer Lett., 1998, 133(1):19-26.
[16] Sugiyama T, Sadzuka Y, et al. Membrane transport and antitumor activity of pirarubicin, and comparison with those of doxorubicin. Jpn [J]. Cancer Res., 1999, 90(7): 775-780.
[17] Sadzuka Y, Sugiyama T, Sonobe T.Improvement of idrarubicin induced antitumor activity and bone marrow suppression by theanine, a component of tea. Cancer Lett., 2000, 158(2): 119-24.
[18] Sugiyama T, Sadzuka Y.Combination of theanine with doxorubicin inhibits hepatic metastasis of M5076 ovarian sarcoma. Clin. Cancer Res., 1999, 5(2): 413-416.
[19] Sugiyama T, Sadzuka Y, et al. Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin. Toxicol Lett., 2001, 121(2): 89-96.
[20] Sadzuda Y, Sugiyama T, et al. Enhancement of the activity of doxorubicin by inhibition of glutamate transporter. Toxicol Lett., 2001, 123(2-3):159-167.
[21] 矢崎一三. 茶の機能, 村松敬一郎等编, 东京: 学会出版センター, 2002: 336-337.
[22] 茶山和敏. 茶の機能, 村松敬一郎等编, 东京: 学会出版センター, 2002: 205-209.
[23] 杉山公男. 茶の機能, 村松敬一郎等编, 东京: 学会出版センター, 2002: 230-233.
[24] Yokozawa T, Dong E.Influence of green tea and its three major components upon low-density lipoprotein oxidation. Exp. Toxicol. Pathol.,1997, 49(5): 329-335.
[25] 商业部茶叶畜产局、杭州茶叶加工研究所编著. 茶叶品质理化分析, 上海: 上海科学技术出版社, 1989: 365-366.
[26] 王三永, 李晓光等. L-茶氨酸的合成研究. 精细化工, 2000, 18(4): 223-224
[27] 钟俊辉,陶文沂.茶愈伤组织培养及茶氨酸的积累. 无锡轻工大学学报. 1997, 16: 1-7
[28] 陈瑛, 陶文沂.几种激素对茶茶愈伤组织合成茶氨酸的影响. 无锡轻工大学学报. 1998,17: 74-77
[29] Tachiki T, Yamada T, et al. γ-Glutamyl transfer reactions by glutaminase from pseudomonas nitroreducens IFO 12694 and their application for the syntheses of theanine and γ-glutamylmethylamide. Biosci. Biotech. Biochem., 1998, 62(7): 1279-1283.
浙公网安备 33019902000101号 
