The animal models were established that different-induced cathartics were fed to different groups of mice respectively to cause diarrhea and mice small intestinal motility. Fuzhuan tea extract was fed to all of the diarrhea mice. The effect of Fuzhuan tea extract on secretion diarrhea, non-infected exudative diarrhea, permeability diarrhea and diarrhea caused by small intestine motility function disorder was investigated. The results showed that Fuzhuan tea extract could reduce the diarrhea index and watery defecate rate caused by senna, castor oil, bitter salt. It could restrain the movement of gastrointestinal tract of the normal mice and the mice whose small intestine motility function disordered. The relationship between the function and the dose was positive.