[1] 宛晓春. 茶叶生物化学(第三版)[M]. 北京: 中国农业出版社, 2003, 9~15.
[2] 唐传核. 植物功能性食品[M]. 北京: 化学工业出版社, 2004, 324~364.
[3] 沈生荣, 杨贤强, 贾春友. 油溶性茶多酚对色拉油的抗氧化作用[J]. 茶叶, 1998, 24(3): 134~137.
[4] 陈理, 孙东. EGCG棕榈酸酯对人卵巢癌HO-8910细胞株的体外抑制活性实验研究[J]. 医学研究杂志, 2006, 35(3): 39~40.
[5] Sang S, Lambert JD, Yang CS.Bioavailability and stability issues in understanding the cancer preventive effects of tea polyphenols[J]. J Sci Food Agric, 2006, 86(14): 2256~2265.
[6] Chen ZY, Zhu QY, Tsang D, et al. Degradation of green tea catechins in tea drinks[J]. J Agric Food Chem, 2001, 49(1): 477~482.
[7] Zhu QY, Zhang A, Tsang D, et al. Stability of green tea catechins[J]. J Agric Food Chem, 1997, 45(12): 4624~4628.
[8] Henning SM, Niu Y, Lee NH, et al. Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement[J]. Am J Clin Nutr, 2004, 80(6): 1558~1564.
[9] 陈平, 孙东, 郑小明. EGCG肉豆蔻酸酯的制备、结构及其抗氧化活性[J]. 浙江大学学报(理学版), 2003, 30(4): 422~425.
[10] Tanaka T, Kusano R, Kouno I.Synthesis and antioxidant activity of novel amphipathic derivatives of tea polyphenol[J]. Bioorga&Med Chem Lett, 1998, 8(6): 1801~1806.
[11] Yano S, Fujimura Y, Umeda D, et al. Relationship between the biological activities of methylated derivatives of (-)-epigallocatechin-3-O-gallate(EGCG) and their cell surface binding activities[J]. J Agric Food Chem, 2007, 55(17): 7144~7148.
[12] Meng X, Sang S, Zhu N, et al. Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats[J]. Chem Res Toxicol, 2002, 15: 1042~1050.
[13] Sakai M, Suzuki M, Nanjo F, ,et al. 3-O-acylated catechins. 3-O-acylated catechins and method of producing same. European Patent, 0618203A1.1994-10-05.
[14] Moon YH, Lee JH, Ahn JS, et al. Synthesis, structure analyses, and characterization of novel epigallocatechin gallate (EGCG) glycosides using the glucansucrase from leuconostoc mesenteroides B-1299CB[J]. J Agric Food Chem, 2006, 54(4): 1230~1237.
[15] Sato T, Nakagawa H, Kurosu J, et al. α-Anomer-selective glucosylation of (+)-catechin by the crude enzyme, showing glucosyl transfer activity, of Xanthomonas campestris WU-9701[J]. J Biosci Bioeng, 2000, 90(6): 625~630.
[16] 石碧, 狄荧. 植物多酚[M]. 北京: 科学出版社, 2000.
[17] 李卫, 宁正祥. 黄酮类化合物的分子修饰[J]. 食品科学, 2005, 26(8): 505~507.
[18] 杨贤强, 王岳飞, 陈留记, 等. 茶多酚化学[M]. 上海科学技术出版社, 2003, 454~455.
[19] 高永贵, 王岳飞, 杨贤强, 等. 脂溶性茶多酚抗油脂氧化及其增效剂的研究[J]. 中国粮油学报, 2000, 15(3): 54~58.
[20] 沈生荣, 金超芳, 杨贤强. 儿茶素的分子修饰[J]. 茶叶, 1999, 25(2): 76~79.
[21] 王巧娥, 唐安斌, 石碧, 等. 脂溶性茶多酚的合成及其抗油脂自动氧化特性的研究[J]. 开然产物研究与开发, 2001, 13(4): 12~15.
[22] 丁玲, 屠幼英, 陈晓敏. 分子修饰后的儿茶素生物活性研究现状[J]. 茶叶科学技术, 2005(1): 1~3.
[23] 张怡, 房诗宏. 茶多酚类抗氧化剂的改性[J]. 食品科学, 2001, 22(2): 88~92.
[24] Tobiason FL.MNDO and AMI molecular orbital and molecular mechanics analyses of (+)-catechin, (-)-epicatechin and their 3-O-acetyl derivatives[J]. Basic Life Sci, Plant Polyphenols, 1992, 59: 459~478.
[25] Patti A, Piattelli M, Nicolosi G.Use of Mucor miehei lipase in the preparation of long chain 3-O-acylcatechins[J]. J Mol Catal B: Enzym, 2000, 10: 577~582.
[26] Uesato S, Kitagawa Y, Hara Y, et al. Antitumor promoting activities of 3-O-acyl-(-)epigallocatechins[J]. Bioorg Med Chem Lett, 2000, 10(15): 1673~1675.
[27] Matsubara K, Saito A, Tanaka A, et al. Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis[J]. DNA Cell Biol, 2006, 25(2): 95~103.
[28] Chen L, Lee MJ, Li H, et al. Absorption, distribution, elimination of tea polyphenols in rats[J]. Drug Metab Dispos, 1997, 25(9): 1045~1050.
[29] Lambert JD, Lee MJ, Lu H, et al. Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice[J]. J Nutr, 2003, 133: 4172~4177.
[30] Bravo L.Polyphenols: chemistry, dietary sources, metabolism and nutritional significance[J]. Nutr Rev, 1998, 56(11): 317~333.
[31] Kohri T, Matsumoto N, Yamakawa M, et al. Metabolic fate of (-)-[4-3H]epigallocatechin gallate in rats after oral administration[J]. J Agric Food Chem, 2001, 49(8): 4102~4112.
[32] Hong J, Lambert JD, Lee SH, et al. Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites[J]. Biochem Biophys Res Commun, 2003, 310: 222~227.
[33] Lam WH, Kazi A, Kuhn DJ, et al. A potential prodrug for a green tea polyphenol proteasome inhibitor: evaluation of the peracetate ester of (-)-epigallocatechin gallate [(-)-EGCG][J]. Bioorga&Med Chem, 2004, 12(21): 5587~5593.
[34] Lambert DJ, Sang S, Hong J, et al. Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate[J]. Drug Metab Dispos, 2006, 34(12): 2111~2116.
[35] Landis-Piwowar KR, Huo C, Chen D, et al. A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate as a potential anticancer agent[J]. Cancer Res, 2007, 67(9): 4303~4310.
[36] Landis-Piwowar KR, Kuhn DJ, Wan SB, et al. Evaluation of proteasome-inhibitory and apoptosis-inducing potencies of novel (-)-EGCG analogs and their prodrugs[J]. Int J Mol Med, 2005, 15(4): 735~742.
[37] Kuhn DJ, Lam WH, Kazi A, et al. Synthetic peracetate tea polyphenols as potent proteasome inhibitors and apoptosis inducers in human cancer cells[J]. Front Biosci, 2005, 10: 1010~1023.
[38] Osanai K, Landis-Piwowar KR, Dou QP, et al. A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer[J]. Bioorga&Med Chem, 2007, 15(15): 5076~5082.
[39] Osanai K, Huo C, Landis-Piwowar KR, et al. Synthesis of (2R,3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, and evaluation of its proteasome inhibitory activities[J]. Tetraedron, 2007, 63(32): 7565~7570.
[40] Ferreira D, Marais JPJ, Slade D.Heterogeneity of the interflavanyl bond in proanthocyanidins from natural sources lacking C-4 (C-ring) deoxy flavonoid nucleophiles[J]. Phytochemistry, 2005, 66(18): 2216~2237.
[41] Saito A, Mizushina Y, Ikawa H, et al. Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases[J]. Bioorga&Med Chem, 2005, 13(8): 2759~2771.
[42] 刘屏, 穆丽华, 韩亚亮, 等. 鸡血藤活性化合物儿茶素结构修饰及抗辐射作用研究[J]. 解放军药学报, 2007, 23(5): 321~324.
[43] 江和源. 表没食子儿茶素没食子酸酯乙酰化物的制备方法. 中国专利, 101190910A.2008-06-04.
[44] 徐向群, 程启坤, 王华夫. 茶多酚油溶剂型的抗氧化活性研究[J]. 食品科学, 1996, 17(5):7~9.
[45] 熊谷彩子. (-)-表没食儿茶素脂肪酸转导体的抗促癌活性[J]. 国外医学: 中医药分册, 2003, 25(5): 316.
[46] 陈平, 钟建华, 孙东. 脂溶性茶多酚中的主要活性组分及对人卵巢癌HO-8910细胞株的体外抑制活性[J].茶叶科学, 2003, 23(2): 115~118.
[47] Folkman J.Angiogenesis in cancer, vascular, rheumatoid and other diseases[J]. Nature Med, 1995, 1: 27~31.
[48] Matsubara K, Saito A, Tanaka A, et al. Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis[J]. Life Sci, 2007, 80(17): 1578~1585.
[49] 来伟旗, 陈建国, 梅松, 等.脂溶性茶多酚调节血脂作用实验研究[J]. 职业与健康, 2007, 23(7): 510~511.
[50] Nakagawa K, Fujii S, Ohgi A, et al. Antioxidative activity of 3-O-octanoyl-(+)-catechin, a newly synthesized catechin, in vitro[J]. J Health Sci, 2005, 51(4): 492~496.
[51] 李炎武, 谭卫兵, 邝雪英, 等. 泛素调节的蛋白质降解-2004年诺贝尔化学奖简介[J]. 化学教育, 2004(11): 30~32.
[52] Sun CL, Yuan JM, Koh WP, et al. Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies[J]. Carcinogenesis, 2006, 27(7): 1310~1315.
[53] Huo C, Shi G, Lam WH, et al. Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract[J]. Can J Chem, 2008, 86(6): 495~502.
[54] Katunuma N, Ohashia A, Sano E, et al. Catechin derivatives: Specific inhibitor for caspases-3, 7 and 2, and the prevention of apoptosis at the cell and animal levels[J]. FEBS Lett, 2006, 580(3): 741~746.
[55] Lee SC, Chan WK, Lee TW, et al. Effect of a prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate on the growth of androgen-independent prostate cancer in vivo[J]. Nutr Cancer, 2008, 60(4): 483~491.
[56] Utenova BT, Malterud KE, Rise F.Antioxidant activity of O-protected derivatives of (-)-epigallocatechin-3-gallate: inhibition of soybean and rabbit 15-lipoxygenases[J]. ARKIVOC, 2007, (ix): 6~16.
[57] Anderson KM, Seed T, Meng J, et a1. Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid[J]. Anticancer Res, 1998, 18(2A): 791~800.
[58] 廖晖, Banbury LK, Leach DN, et al. 12味止血中药对脂多糖诱导小鼠巨噬细胞产生一氧化氮的抑制作用[J]. 中国药房, 2007, 18(9): 649~651.
[59] 张晶, 郑毅男, 刘桂英. 抑制花生四烯酸代谢活性中药研究现状[J]. 天然产物研究与开发, 2001, 13(4): 83~87.
浙公网安备 33019902000101号 
