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茶叶科学 ›› 2007, Vol. 27 ›› Issue (3): 221-225.doi: 10.13305/j.cnki.jts.2007.03.015

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藤茶总黄酮及二氢杨梅素降血脂作用研究

陈玉琼1, 倪德江1, 程倩1, 黄海波1, 孟燕1, 吴谋成2   

  1. 1. 农业部亚热带农业资源与环境重点开放实验室,华中农业大学园艺林学学院,湖北 武汉 430070;
    2. 华中农业大学食品科技学院,湖北 武汉 430070
  • 收稿日期:2007-01-08 修回日期:2007-04-26 出版日期:2007-09-25 发布日期:2019-09-11
  • 作者简介:陈玉琼(1968— ),女,重庆人,副教授,博士,主要从事茶用植物功能化学及综合利用的教学与研究。
  • 基金资助:
    农业部农业结构调整重大技术研究专项; 项目编号:06-08-02B

Study on the Hypolipidemic Effect of Flavones and Dihydromyricetin From Tengcha

CHEN Yu-qiong1, NI De-jiang1, CHENG Qian1, HUANG Hai-bo1, MENG Yan1, WU Mou-cheng2   

  1. 1. Key Lab of Subtropical Agriculture Resource and Environment MOA, College of Horticulture and Forestry Sciences Huazhong Agricultural University, Wuhan 430070, China;
    2. College of Food Science and Technology of Huazhong Agricultural University, Wuhan 430070, China
  • Received:2007-01-08 Revised:2007-04-26 Online:2007-09-25 Published:2019-09-11

摘要: 本文探讨了藤茶中主要活性成分黄酮及二氢杨梅素对高血脂症小鼠的降血脂效果。结果表明:与高脂模型组比较,二氢杨梅素对高脂血症小鼠体重有明显减轻作用;黄酮及二氢杨梅素都能不同程度降低小鼠血清TC、TG、LDL-C、MDA含量,提高血清HDL-C含量及SOD活性,降低肝系数。肝脏病理学观察表明,喂饲藤茶黄酮及二氢杨梅素组小鼠肝细胞变性、肿胀的程度减轻。说明藤茶黄酮及二氢杨梅素能降低小鼠血脂,增强机体抗氧化能力,减轻高脂对肝细胞的损伤作用。

关键词: 藤茶, 黄酮, 二氢杨梅素, 降血脂, 抗氧化

Abstract: The effects of Tengcha flavones and dihydromyricetin(DMY) on hypolipidemic mice were investigated. The results showed, compared with the hyperlipidemia control group, DMY reduced the weights of mice significantly; Tengcha flavones and DMY decreased serum TC、TG、LDL-C、malondiadehyde(MDA) contents and Liver coefficient, increased HDL-C levels and the activities of SOD distinctly. The pathological observation on the liver tissue showed that Tencha flavones and DMY could lighten the denaturation liver cell. As results, Tengcha flavones and DMY could prevent hypolipidemia in mice and protect myocardial cells from oxidation and the liver harmful from of high lipid.

Key words: ampelopsis-grossedentata, flavone, Dihydromyricetin, hypolipidemic, antioxidation

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