探讨了湖北青砖茶对高血脂症大鼠的降血脂效果,并与绿茶进行了比较。结果表明：与模型组比较,贮藏1年和10年的青砖茶、血脂康、绿茶都能极显著降低大鼠体重及血清TC、TG和MDA含量,提高血清HDL-C含量和血清SOD、GSH-PX活性,降血脂效果明显。其中,青砖茶降脂效果优于血脂康和绿茶,10年青砖茶优于1年青砖茶,1年青砖茶各剂量的降脂效果具有剂量依赖关系,随喂饲剂量的增加,降脂效果提高。肝脏病理学观察表明,各受试药物组大鼠肝细胞变性、肿胀的程度减轻,以1年青砖高剂量组及10年青砖剂量组大鼠肝脏保护最好,说明青砖茶能有效降低大鼠血脂,增强机体抗氧化能力,减轻高脂对肝细胞的损伤作用。
The effects of Hubei Qingzhuan tea on hypolipidemic rats were investigated. The results showed, compared with the hyperlipidemia control group, each tested group had significant reduction in the body weight of rats, the serum TC、TG and malondiadehyde(MDA) contents, and marked increase in the level of HDL-C , the activities of SOD and GSH-PX. On the effects of decreasing serum lipids, Qingzhuan tea was more significant than that of Xuzikang—a blood lipid decreasing medicine, and green tea, Qingzhuan tea stored for 10 years was more significant hypolipidemic effect than Qingzhuan tea stored for 1 year. The pathological observation on the liver tissue showed that each tested sample could lighten the denaturation liver cell. We conclude that Qingzhuan tea showed the effect of body weight decreasing, serum lipids decreasing, antioxidation increasing and liver cells protecting of hypolipidemic rats.
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