To evaluate the edible safety of anti-radiation preparations of tea polyphenol, the experiment included acute toxicity test, Ames test, micronucleus test, sperm shape abnormality test and thirty days feeding test were performed. Results showed that the oral maximum tolerance dose(MTD) was higher than 20.0 g/kg·bw both in female and male mice and rats. The results on toxicity of Ames test, micronucleus test, sperm shape abnormality test and mutagencity were negative. No toxicological symptom was appeared in tested animals from thirty days feeding test. It is concluded that the anti-radiation preparations of tea-polyphenol was classified as non-toxicology and genotoxicity, high edible safety.
WANG Yue-fei
,
LIANG Shan-zhu
,
ZHANG Shi-kang
,
CHEN Hong-bo
,
ZHU Yue-jin
,
HUANG Shuang-ru
,
YANG Xian-qiang
. Study on the Toxicology of an Anti-radiation Preparation of Tea-polyphenols[J]. Journal of Tea Science, 2011
, 31(5)
: 405
-410
.
DOI: 10.13305/j.cnki.jts.2011.05.002
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