The experiment of three different doses of instant Fuzhuan tea (0.085βg/kg·bw, 0.170βg/kg·bw and 0.510βg/kg·bw) Feed on the Wistar mouse for 30 days were conducted. The results showed that Fuzhuan tea had the effect of decreasing the body weight, TC, TG and increasing the HDL-C. The Fuzhuan tea beverage processed by the method of extracting the tea for 1 hour with the ratio of 1:1000 of tea to water. The beverage was drank by volunteers with the dose of 1β000βml/day for 34 days, the content of TC and TG in drinker decreased significantly, the content of LDL-C also decreased, and the content of HDL-C increased significantly. All the drinker felt fine, and their blood general index, blood sugar index and liver and kidney function all were normal. The beverage was stable for 90 days storage, all indexs were accord with the national hygeian standard. All results suggested Fuzhuan tea showed beneficial effect on the regulation of blood lipid.