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Effect of Pu-erh Tea on Long Chain Fatty Acid Metabolism and Expression of Tight Junction Proteins in the Rat Model of Non-alcoholic Fatty Liver Disease

  • ZHU Shengyi ,
  • TONG Yuling ,
  • ZHAO Yi ,
  • LÜ Haipeng ,
  • LIN Zhi ,
  • SHEN Guoli ,
  • SUN Ting ,
  • SONG Zhenya
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  • 1. The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China;
    2. Key Laboratory of Tea Biology and Resource Utilization of Ministry of Agriculture, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China

Received date: 2015-12-21

  Online published: 2019-08-23

Abstract

In this study, the influence of Pu-erh tea on the absorption of long chain fatty acids in non-alcoholic fatty liver disease (NAFLD) rats was analyzed. Moreover, the possible interventional mechanism was also discussed. Thirty-six SD rats were randomly divided into three groups, normal group (NG), NAFLD group, and Pu-erh tea group (PTG), 12 rats for each group. All rats were killed after 8 weeks. Rat weight, liver index, serum lipid level, intestinal lipid absorption protein (CD36), tight junction proteins (Occludin, ZO-1), and TNF-α mRNA were measured.

Cite this article

ZHU Shengyi , TONG Yuling , ZHAO Yi , LÜ Haipeng , LIN Zhi , SHEN Guoli , SUN Ting , SONG Zhenya . Effect of Pu-erh Tea on Long Chain Fatty Acid Metabolism and Expression of Tight Junction Proteins in the Rat Model of Non-alcoholic Fatty Liver Disease[J]. Journal of Tea Science, 2016 , 36(3) : 237 -244 . DOI: 10.13305/j.cnki.jts.2016.03.002

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