茶红素化学及生物学活性研究进展

doi:10.13305/j.cnki.jts.2013.04.006

摘要/Abstract

摘要： 茶红素是一类异质的酸性酚性色素的总称,其主要前体物为儿茶素和茶黄素类。它与红茶的色泽、汤色、浓度和强度等品质密切相关。由于茶红素的异质性,其溶解性和色谱学性质相差较大,化学结构还不清楚。目前茶红素主要制备方法仍然是经典的有机溶剂分级提取法。尽管茶红素单体的分离纯化尚未见诸报道,但自上世纪九十年代以来,研究者在体外实验和动物学研究中发现,茶红素与儿茶素、茶黄素相比,存在一些相似的生物学活性,如抗氧化、抗癌、抗肿瘤、抗突变、抗炎、抗白血病、预防肥胖,甚至有抗神经毒素作用。茶红素作为红茶中含量最为丰富的多酚类物质,可能对人体健康有着积极的作用。

关键词: 红茶, 茶红素, 结构, 生物学活性

Abstract: Thearubigins are mixtures of heterogeneous acidic phenolic pigments, which are condensed oligomers or polymers from catechins and theaflavins. Thearubigins contribute to tea color, the body strength, intensity and liquor color of a black tea brew. Due to their heterogeneity, their solubility and chromatographic behaviors are dissilimar and their structures are still ambiguous. The classic isolation method of the thearubigin subfractions has been developed with organic solvent extraction. So far, no thearubigin monomer has been reported. However, some studies have demonstrated that thearubigins possess antioxidative, anti-tumor, anti-mutagenic, anti-carcinogenic, anti-inflammatory, anti-leukemic, obesity-preventive and even anti-neurotoxin activities in vitro and in animal models since 1990s. As the abundant polyphenolic compounds in black tea, thearubigins may be the potential active compounds contributing to human health.

Key words: black tea, thearubigins, structure, bioactivity

中图分类号:

李大祥, 王华, 白蕊, 鲜殊, 宛晓春. 茶红素化学及生物学活性研究进展[J]. 茶叶科学, 2013, 33(4): 327-335. doi: 10.13305/j.cnki.jts.2013.04.006.

LI Da-xiang, WANG Hua, BAI Rui, XIAN Shu, WAN Xiao-chun. The Chemistry and Bioactivity of Thearubigins[J]. Journal of Tea Science, 2013, 33(4): 327-335. doi: 10.13305/j.cnki.jts.2013.04.006.

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