Journal of Tea Science ›› 2003, Vol. 23 ›› Issue (2): 83-93.doi: 10.13305/j.cnki.jts.2003.02.001
CHEN Zong-mao
Online:
2003-11-25
Published:
2019-09-16
CLC Number:
CHEN Zong-mao. Biochemical and Molecular Biological Basis on The Anticarcinogenic Activity of Tea Polyphenolic Compounds[J]. Journal of Tea Science, 2003, 23(2): 83-93.
[1] 陈宗懋. 茶叶抗癌的生物化学基础[J]. 中国肿瘤, 2000, 9:23-25. [2] 陈宗懋. 20世纪茶与健康研究的主要进展[J],中国茶叶,2001, 23:8-10. [3] J L Bushman. Green tea and cancer in humans: A review of the literature[J]. Nutrition & Cancer, 1998, 31:151-159. [4] H Fujiki et al. Mechanistic findings of green tea as cancer preventive for humans[J]. Proceed Soc Exp Biol Med, 1999, 220:225-228. [5] Y Kuroda & Y Hara. Antimutagenic and anticarcinogenic activity of tea polyphenols[J]. Nut Res, 1999, 36:69-97. [6] C S Yang et al. Inhibition of carcinogenesis by dietary polyphenolic compounds[J]. Ann. Rev. Nutr., 2001, 21:381-406. [7] S I Trevisanato. Tea and health[J]. Nutr. Rev., 2000, 58:1-10. [8] H Mukhtar & N Ahmad. Green tea in chemoprevention of cancer[J]. Toxicol. Sci., 1999, 52(suppl.):111-117. [9] Lin J K & Liang Y C. Cancer prevention by tea polyphenols[J]. Proc. Natl. Sci. Coun, (B), Biol. Sci., 2000,24:1-13. [10] Wang Y C & U Bachrach. The specific anti-cancer activity of green tea EGCG[J]. Amino Acids, 2002, 22:131-143. [11] S K Katiyar & H M Mukhtar. Tea in chemoprevention of cancer: Epidemiologic and experimental studies (Review) [J]. Internat. J. Oncology, 1996,8:221-238. [12] W J Blot et al. Tea and cancer: A review of the epidemiological evidence[J]. Eur. J Can. Preven., 1996, 5:425-438. [13] L Kohlmeier et al. Tea and cancer prevention: An evaluation of the epidemiologic literature[J]. Nut. & Can., 1997, 27:1-13. [14] Yang C A et al. Effects of tea on carcinogenesis in animal models and humans[A], In “Dietary phytochemicals in cancer prevention and treatment” [C]. pp.51-61, Plenum Press, New York,1996. [15] Nakachi K et al. Influence of drinking green tea on breast cancer malignancy among Japenese patients[J]. Jp. J Can. Res., 1998, 89:254-261. [16] Cao G et al. Antioxidant capacity of tea and common vegetables[J]. J. Agricul. Fd. Chem., 1996, 44:3426-3431. [17] Rice-Evans C et al. Antioxidant properties of phenolic compounds[J]. Trends in Pl. Sci., 1997, 2:512-159. [18] Lee S R et al. Protective effect of green tea polyphenol (-)EGCG and other antioxidants on lipid peroxidation in gerbil brain homogenerates[J]. Phytother. Res., 2003, 17:206-209. [19] Kiyoka H O et al. Potent antioxidative activity of non-polyphenolic fraction of green tea-associated with pheophytins a and b[J]. J Sci. Fd. Agricul., 2000, 80:117-120. [20] I Naasani et al. Blocking telomerase by dietary polyphenols ia a major mechanism for limiting the growth by human cancer cells in vitro and in vivo[J]. Cancer Res., 2003, 63:824-830. [21] Wang Z Y et al. Interaction of epicatechins derived from green tea with rat hepatic cytochrome P450[J]. Drug Metab. Dispos., 1998, 16:98-103. [22] Agarwal R et al. Inhibition of tumor promoter-caused induction of ornithine decarboxylase activity in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives[J]. Cancer Res., 1992, 52:3582-3588. [23] 胡秀芳, 等. 茶多酚抗氧化机理研究现状,茶叶科学,1999,19(2):93-103. [24] J Hong et al. Effects of purified green and black tea polyphenols on cycloxygenas- and lipoxygenase-depedent metabolism of arachidonic acid in human colon musoca and colon tumor tissues[J]. Biochem. Pharmacol., 2001, 62:1175-1183. [25] B Annabi et al. Green tea polyphenol (-)EGCG inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells[J]. Biochim. Et Biophy. Acta, 2002, 1542:209-220. [26] J Jankun et al. Why drinking green tea could prevent cancer[J]. Nature, 1997, 387:561. [27] S Garbisa et al. Tumor gelatinases and invasion inhibited by the green tea flavanol EGCG[J]. Cancer, 2001, 91:822-832. [28] L Sartor et al. (-)EGCG inhibits leukocyte elastase: potential of the phyto-factor in hindering inflammation, emphysema and invasion[J]. J Leuk. Biol., 2002, 71:71-79. [29] R A Hiipakka et al. Structure-activity relationships for inhibition of human 5α-reductase by polyphenols[J]. Biochem. Pharmacol., 2002, 63:1165-1176. [30] Gupta S et al. Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated industion of ornithine decarboxylase in mice[J]. Cancer Res., 1999, 59:2115-2120. [31] U Bachrach & Y C Wang. Cancer therapy and prevention by green tea: role of ornithine decarboxylase[J]. Amino Acids, 2002, 22:1-13. [32] Khan S G et al. Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention[J]. Cancer Res., 1992, 52:4050-4052. [33] N Ahmad et al. Nitric oxide synthase and skin tumor promotion[J]. Bioch. & Biophy. Res. Commun., 1997, 232:328-331. [34] J Y Chung et al. Inhibition of activator protein 1 activity and cell growth by pirified green and black tea polyphenols in H-ras transformed cells: structure-activity relationship and mechanism involved[J]. Cancer Res., 1999, 59:4610-4617. [35] S Pianetti et al. Green tea polyphenol EGCG inhibits Her-2/Neu signaling, proliferation and transformed phenotype of breast cancer cells[J]. Can. Res., 2002, 62:652-655. [36] Pan M H et al. Suppression of lipopolysaccharide-induced nuclear factor-kβactivity by theaflavin-3,3’digallate from black tea and other polyphenols through down regulation of Ik B kinase activity in macrophage[J]. Biochem. Phamacol., 2000, 59:357-367. [37] Liang Y L et al. Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)EGCG in human A-431 epidermoid carcinoma cells, J Cellu. Biochem., 1997, 67:55-65. [38] Dong Z et al. Inhibition of tumor promotor-induced activator protein 1 activation and cell transformation by tea polyphenols (-)EGCG and theaflavins[J]. Can.Res. 1997, 57:4414-4419. [39] Lin J K et al. Cancer prevention by tea polyphenols through mitotic signal transduction blockage[J]. Biochem. Pharmacol., 1999, 58:911-918. [40] S K Katiyar et al. Inhibition of UVB-induced oxidative stress-mediated phosphorylation of mitogen-activated protein kinase signaling pathways incultured human epidermal keratinocytes by green tea polyphenolic (-)EGCG[J]. Toxicvol. & Appl Pharmacol., 2001, 176:110-117. [41] Hee-Yul Ahn et al. EGCG selectivity inhibits the PDGF-BB induced intracellular signaling transduction pathway in vascular smooth musclle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172) [J]. Mol. Biol. of Cells, 1999, 10:1093-1104. [42] Lin Y L et al. EGCG blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nucluear factor-KB, Molec[J]. Pharmacol., 1997, 52:465-472. [43] F Afag et al. Inhibition of of ultraviolet B-mediated activation of nuclear factor kB in normal epidermal keratinocytes by green tea constituent (-)EGCG[J]. Oncogene, 2003, 22:1035-1044. [44] J Folkman. Tumor angiogenesis: therapeutic implications[J]. N. Engl. J Med., 1973, 285:1182-1186 [45] Y Cao et al Antiangiogenic mechanisms of diet-derived polyphenols[J]. J Nutr. Biochem., 2002, 13:380-390. [46] M Sartippour et al. Inhibition of fibroblast growth factors by green tea[J]. Internat. J. Oncology, 2002, 21:487-491. [47] S Lamy et al. Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation[J]. Cancer Res., 2002, 62:381-385. [48] F Tosetti et al. Angioprevention: angiogenesis isa common and key target for cancer chemopreventive agents[J]. FASEB J, 2002, 16:2-14. [49] Y Zhao et al. Apoptosis induced by tea polyphenols in HL-60 cells[J]. Cancer Lett.,1997, 121:163-167. [50] N Ahmad et al. Green tea constituent EGCG and induction of apoptosis and cell cycle arrest in human carcinoma cells[J]. J. Natl. Cancer Inst., 1997, 89:1881-1886. [51] A G Paschka et al. Induction of apoptosis in postate cancer cell lines by the green tea component, EGCG[J]. Cancer Lett., 1998, 130:1-7. [52] Yang G Y et al. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols[J]. Carcinogenesis, 1998, 19:611-616. [53] S Gupta et al. Growth inhibition, cell cycle dysesgulation and induction of apoptosis by green tea constituent EGCG in androgen-sensitive and androgen-insensitive human prostate carcinoma cells[J]. Tox. Appl. Pharmacol., 2000, 164:82-90. [54] Zheng G Y et al. Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas[J]. Nutr. & Cancer 2000, 38:265-273. [55] S Gupta et al. Molecular pathway for (-)EGCG-induced cell cycle arrest annd apoptosis of human prostate carcinoma cells[J]. Archiv. Biochem. Biophy., 2003, [56] Okabe S et al. Mechanisms of growth inhibition of human lung cancer cell line PC-9 by tea polyphenols[J]. Jp. J. Cancer Res., 1997, 88:639-643. [57] Hibasani H et al. Induction of programmed cell death (apoptosis) in human lymphrid leukemia cells by catechin compounds[J]. Anticanc. Res., 1996, 16:9943-1946. [58] 胡秀芳、杨贤强. 茶儿茶素对癌细胞凋亡作用的研究[J]. 茶叶科学,2001,21:(1)26-29. [59] Fujiki H. Two stages of cancer prevention with green tea[J]. J Cancer Res Clin Oncol, 1999, 125:589-597. [60] M Saganuma et al. Synergistic effects of (-)EGCG with (-) epicatechin, Sulindac or Tamoxifen on cancer preventive activity in the human lung cancer cell line PC-9[J]. Cancer,Res., 1999, 59:44-47. [61] H Fujiki et al. New TNF-α releasing inhibition as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and Sulindac or Tamoxifen[J]. Mut. Res., 2003, 523-524:119-125. [62] H Fujiki et al. Green tea: Cancer preventive beverage and/or drug[J]. Cancer Lett., 2002, 188:9-13. [63] CHEN L S et al. Absorption, distribution and elimination of tea polyphenols in rats[J]. Drug Metab. Dispos., 1999, 25:1045-1050. [64] Yang C S et al. Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers[J]. Canc. Epidem., Biomar. & Prev., 1998, 7:351-354. [65] 陈清泉. 茶儿茶素之吸收及代谢[J]. 食品工业会志,2001, 33:1-14. [66] J M M Van Amelavoort et al. Plasma concentration of individual tea catechins after a single oral dose in humans[J]. Xenobiotica, 2001, 31:891-901. [67] Yang C A et al. Human salivary tea catechin levels and catechin esterase activities: impliucation in human cancer prevention studies[J]. Cancer Epidem. Biomark. & Prev., 1999, 8:83-89. [68] Meng X F et al. Formation and identification of 4-O-methyl-(-)EGC in humans[J]. Drug Metab. Dispos., 2001, 29:789-793. [69] Kida K et al. Identification of bililary metabolites of (-)EGCG in rats[J]. J Agricul Fd Chem, 2000, 48:4151-4155. [70] Tachibana H et al. Identification of a methylated tea catechin as an inhibitor of degranulation in human basophilic KU812 cells[J]. Biosci. Biotech. Biochem., 2000, 64: 4522-4524. [71] M Piskula & J.Terao. Accumulation of (-)epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues[J]. J Nutr, 1998, 128:1172. [72] 山本万里. 绿茶の抗ァレルギ-作用とがん转移阻害效果[J]. 日本食品科学工业会志2002, 49:631-638. |
[1] | ZHOU Shaofeng, QIAN Yunfei, ZHAO Zhen, CHEN Xuan, LI Xinghui. Effect of the Tea with Different Degrees of Fermentation on the Formation of Tea Scum [J]. Journal of Tea Science, 2022, 42(1): 76-86. |
[2] | WU Xin, SONG Feihu, PEI Yongsheng, ZHU Guanyu, JIANG Lebing, NING Wenkai, LI Zhenfeng, LIU Benying. Study on the Tea Quality Changes and Predictions during the Microwave Fixation Process by Machine Vision [J]. Journal of Tea Science, 2021, 41(6): 854-864. |
[3] | XIONG Xingping, ZHANG Xinzhong, LI Hongbin, SUN Liang, YAO Mingzhe. Analysis on the Achievements of Tea Science and Technology Awards at Provincial and Ministerial Level and above in China from 2008 to 2019 [J]. Journal of Tea Science, 2021, 41(5): 608-618. |
[4] | WANG Shenglin, YANG Chongshan, LIU Zhongyuan, LIU Shanjian, DONG Chunwang. Rapid Detection Method of Tea Polyphenol Content in Black Tea Fermentation Based on Electrical Properties [J]. Journal of Tea Science, 2021, 41(2): 251-260. |
[5] | LU Li, CHENG Xi, ZHANG Bo, SHEN Xiaoxia, LIU Yan, XIONG Li, YUAN Xiao, LI Yuanhua, LI Xinghui. Establishment of Predictive Model for Quantitative Analysis of Tea Polyphenols and Caffeine of Souchong by Near Infrared Spectroscopy [J]. Journal of Tea Science, 2020, 40(5): 689-695. |
[6] | XIONG Xingping, ZHANG Xinzhong, YANG Zhenwei. Analysis of the Tea Projects Supported by National Natural Science Foundation of China from 1999 to 2019 [J]. Journal of Tea Science, 2020, 40(3): 305-318. |
[7] | YAO Min, LI Daxiang, XIE Zhongwen. Recent Advance on Anti-cardiovascular Inflammation of Major Characteristic Compounds in Tea [J]. Journal of Tea Science, 2020, 40(1): 1-14. |
[8] | ZHOU Fang, OUYANG Jian, HUANG Jian'an, LIU Zhonghua. Advances in Research on the Regulation of Tea Polyphenols and Effects on Intestinal Flora [J]. Journal of Tea Science, 2019, 39(6): 619-630. |
[9] | ZHANG Shuping, WANG Yuefei, XU Ping. Prevention of Tea Polyphenols on Atherosclerosis and Relative Mechanisms [J]. Journal of Tea Science, 2019, 39(3): 231-246. |
[10] | ZHU Lin, WU Long, CHEN Xiaoqiang, CHEN Xueling, WU Zhengqi, SHI Yong. Interaction between Tea Polyphenols and Polysaccharides: Progress in Research on Mechanism and Function [J]. Journal of Tea Science, 2019, 39(2): 203-210. |
[11] | WU Genliang, HOU Aixiang, LI Ke, LI Zongjun. Effects of Polyphenols of Old Fu Brick Tea on the Elderly Intestinal Flora [J]. Journal of Tea Science, 2018, 38(3): 319-330. |
[12] | SHI Chunlin, LI Xiaohuan, HUANG Xiangxiang. Effects of Green Tea Polyphenols on Oxidative Stress Induced by Passive Smoking in Mice Lung [J]. Journal of Tea Science, 2018, 38(2): 212-220. |
[13] | LEI Liping, ZHU Yuehua, ZHANG Jian, YANG Wenge, LI Puyou, LIU Yanjie, QIAN Yunxia. Effects of Tea Polyphenols on Quality and Microorganisms of Pseudosciaena crocea during Iced Storage [J]. Journal of Tea Science, 2017, 37(5): 523-531. |
[14] | WEI Ran, XU Ping, YING Le, WANG Yuefei. Progress in the Prevention of Tea Polyphenols on Alzheimer's Disease and Their Mechanisms [J]. Journal of Tea Science, 2016, 36(1): 1-10. |
[15] | LIU Xiaoxiang, SUN Aihua, DU Peng, CHEN Wenhu, ZHU Junli. Cross-resistance Induced by Tea Polyphenols in Pseudomonas aeruginosa [J]. Journal of Tea Science, 2015, 35(6): 534-542. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||
|