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Journal of Tea Science ›› 2020, Vol. 40 ›› Issue (1): 1-14.doi: 10.13305/j.cnki.jts.20191202.004

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Recent Advance on Anti-cardiovascular Inflammation of Major Characteristic Compounds in Tea

YAO Min, LI Daxiang, XIE Zhongwen*   

  1. State Key Laboratory of Tea Plant Biology and Utilization. Anhui Agricultural University, Hefei 230036, China
  • Received:2019-03-26 Revised:2019-07-04 Online:2020-02-15 Published:2020-02-04

Abstract: Chronic inflammation is one of the important causes of cardiovascular diseases such as atherosclerosis, hypertension and myocardial infarction. Inflammatory factors such as IL-6, TNF-α and IL-1β can induce many cardiovascular diseases, including myocardial hypertrophy, myocardial fibrosis and abnormal proliferation of vascular smooth muscle cells. Tea is rich in characteristic compounds. These compounds play preventive and therapeutic roles for cardiovascular diseases by inhibiting proinflammatory cytokines production, and regulating the signal pathways such as NF-κB, MAPK and Tolls-like receptors. In this review, we summarized the recent advance of the main characteristic compounds in tea on preventing inflammation related cardiovascular diseases.

Key words: cardiovascular inflammation, tea polyphenols, signaling pathways, characteristic compounds

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