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Journal of Tea Science ›› 2019, Vol. 39 ›› Issue (6): 619-630.doi: 10.13305/j.cnki.jts.2019.06.001

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Advances in Research on the Regulation of Tea Polyphenols and Effects on Intestinal Flora

ZHOU Fang1,2, OUYANG Jian1,2, HUANG Jian'an1,2,3, LIU Zhonghua1,2,3,*   

  1. 1. Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China;
    2. National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha 410128, China;
    3. Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients, Changsha 410128, China
  • Received:2019-04-29 Revised:2019-07-20 Online:2019-12-15 Published:2019-12-24

Abstract: Metabolic syndrome (MS) is an abnormal multi-metabolic disease that comprises a combination of various diseases such as hypertension, abnormal blood sugar, dyslipidemia and obesity. Tea polyphenols (TPs) are the characteristics secondary metabolites in tea leaves. The latest studies show that TPs can improve the disorder of gut flora (GF) and modulate the co-metabolism of Host-GF by the intervention & treatment to achieve the goal of improving MS. This paper systematically summarized the absorption and metabolism of TPs and the effects of TPs on GF in in vitro fermentation models, animal experiments, and clinical trials. The underlying mechanism among TPs-GF-Host was described, which would facilitate further exploring the effects of TPs on human health based on the theory of intestinal flora and developing functional products of TPs. In addition, it also provided theoretical foundation for developing functional products associating with TPs.

Key words: tea polyphenols, absorption and metabolism, gut flora, metabolic syndrome

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