茶多酚类化合物抗癌的生物化学和分子生物学基础

doi:10.13305/j.cnki.jts.2003.02.001

摘要/Abstract

摘要： 本文对近五年来国际上关于茶多酚类化合物对人体抗癌活性及其机理的研究进展进行了分析和综述。全文分抗氧化活性、对关键酶的调控、阻断信息传递、抗血管形成和细胞凋亡五个方面讨论了其抗癌机理，并对茶多酚今后的开发前景和研究动向进行了讨论。

关键词: 茶学, 生物化学, 分子生物学, 茶多酚, 抗癌机理

Abstract: The progress in the investigation of anticarcinogenic activity of tea polyphenols and its biochemical and molecular biological mechanisms in the world in recent 5 years were analyzed and reviewed in this paper. The mechanism of anticarcinogenic activity was discussed from the following 5 aspects: antioxidative activity, modulation on the key enzymes, blockage of signal transduction, antiangiogenic activity and the apotopsis of cancer cells. The developmental prospect and the investigational tendency of tea polyphenols in the future were discussed.

Key words: Tea science, Biochemistry, Molecular biology, Tea polyphenols, Anticarcinogenic mechanism

中图分类号:

TS201.2
R963

陈宗懋. 茶多酚类化合物抗癌的生物化学和分子生物学基础[J]. 茶叶科学, 2003, 23(2): 83-93. doi: 10.13305/j.cnki.jts.2003.02.001.

CHEN Zong-mao. Biochemical and Molecular Biological Basis on The Anticarcinogenic Activity of Tea Polyphenolic Compounds[J]. Journal of Tea Science, 2003, 23(2): 83-93. doi: 10.13305/j.cnki.jts.2003.02.001.

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