信阳毛尖茶水提物缓解PM2.5致大鼠肺损伤的研究

doi:10.13305/j.cnki.jts.2021.04.006

Abstract

Abstract: In this study, the healthy male sprague-dawley (SD) rats were taken as experimental subjects, and the water extracts of Xinyang Maojian tea were used as test substances, while intratracheal instillation of PM_2.5 suspension was established as chronic pulmonary injury model. Rats serum and biochemical indexes of bronchoalveolar lavage fluid (BALF) were tested. The results show that the tea extracts had antagonism effects on the reduce of rats growth rate and the lung injury caused by PM_2.5. Furthermore, the tea water extracts could effectively lower the increase of IL-1β, IL-6, TNF-α, IgG and the activity of LDH, and keep the activity of SOD in rats serum and BALF, showing a dose-dependent effects.

Key words: Xinyang Maojian tea, alleviate, fine particulate matter, intratracheal instillation, pulmonary injury

CLC Number:

S571
R563

LIU Jianjun, LI Meifeng, ZHANG Jing, TIAN Lili, DENG Yanli, LIN Haiyan, HUANG Jian′an, LIU Zhonghua. A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM_2.5[J]. Journal of Tea Science, 2021, 41(4): 525-534.

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A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM_2.5

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A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM2.5

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A Study of Xinyang Maojian Tea Water Extracts on Relieving Lung Injury Caused by PM_2.5