Abstract: The aim of this study was to investigate the effects of FU brick tea water extracts on the adjustment of intestinal immune function of mice. Lavage with the Ampicillin to establish mice intestinal dysbacteriosis and immune dysfunction model. KM mice were random divided into six groups: normal control, natural recovery group, model group, three dose group of brick tea. The intestinal flora detection, the small intestinal mucous sIgA measurement, the measurement of IL-2 in serum, Serum albumin and total protein content detection and Ileum section pathological detection. The results showed that lavage with the Ampicillin 5βd, alteration of intestinal flora, the small intestinal mucous sIgA, the IL-2 in serum, serum albumin and total protein content were declined significantly compared with the normal saline group, in addition, the Ileum tissue slice showed obvious lesions. Compared with the natural recovery group, the small intestinal mucous sIgA, the IL-2 in serum, serum albumin and total protein content were increased significantly after the treatment with the brick tea water extracts. In the comparison between the treatment groups, the effect of high doses group were much better than the low doses group of treatment. It was concluded that the FU brick tea extracts can repair the damaged mucous membrane, showed the adjustment of the intestinal immune functions.

Key words: Fuzhuan brick tea, immunity intestinal, sIgA, IL-2, intestinal flora