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Journal of Tea Science ›› 2022, Vol. 42 ›› Issue (4): 561-576.doi: 10.13305/j.cnki.jts.2022.04.010

• Research Paper • Previous Articles     Next Articles

Clinical Trial on the Effect of Drinking Jinhua Xiangyuan Tea for 3 Months on the Improvement of Glucose and Lipid Metabolism in A Small Sample Hyperlipidemia Population

SUN Ying1,3,4, CHEN Xin1,3,4, YANG Hua2, YING Jian1,3,4, SHAO Danqing1,3,4,*, LÜ Xiaohua2,*, XIAO Jie1,3,4, CHEN Zhixiong5, LI Song6, QIN Junjie7, ZHENG Bin5, GAO Jianshe5   

  1. 1. Nutrition and Health Research Institute, COFCO Ltd., Beijing 102209, China;
    2. West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China;
    3. Beijing Key Laboratory of Nutrition & Health and Food Safety, Beijing 102209, China;
    4. Beijing Engineering Laboratory for Geriatric Nutrition Food Research, Beijing 102209, China;
    5. Xiamen Tea Import and Export Co., Ltd., Xiamen 361013, China;
    6. China Tea Technology (Beijing) Co., Ltd., Beijing 102209, China;
    7. Shenzhen Puyuan Technology Co., Ltd., Shenzhen 518000, China
  • Received:2022-02-08 Revised:2022-03-17 Online:2022-08-15 Published:2022-08-23

Abstract: This study is aimed at investigating the clinical effect of drinking Jinhua Xiangyuan tea for 3 months on the glucose and lipid metabolism in a small sample patients with hyperlipidemia (with/without non-alcoholic fatty liver). Jinhua Xiangyuan tea was produced by the new process using Eurotium cristatum. In this study, before-and-after control design was used. The body composition (body weight, BMI, waist hip ratio, percentage of body fat, visceral fat grade), blood biochemical indicators (fasting blood glucose, uric acid, blood lipid), fatty liver, and gut microbiota were examined before and after the test. After drinking Jinhua Xiangyuan tea for 3 months, the body weight, BMI, percentage of body fat, visceral fat grade, serum total cholesterol, low-density lipoprotein cholesterol, and fasting blood glucose of 38 volunteers were significantly reduced (P<0.05). Fatty liver was less severe. Gut microbiota’s diversity and richness were increased. The relative abundance of Phascolarctobacterium, Ruminococcus, Haemophilus and Veillonella were increased, and Dialister and Butyricimonas were decreased. Jinhua Xiangyuan tea could increase the relative abundance of short-chain fatty acid-producing bacteria, increasing short-chain fatty acids, and improving insulin resistance, then improving glucose and lipid metabolism. The results of this study still need to be further confirmed by more rigorous long-term experimental observation.

Key words: Jinhua Xiangyuan tea, glucose and lipid metabolism, gut microbiota, short-chain fatty acids

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