饮用金花香橼茶3个月对小样本高脂血症人群糖脂代谢的改善效果研究

doi:10.13305/j.cnki.jts.2022.04.010

Abstract

Abstract: This study is aimed at investigating the clinical effect of drinking Jinhua Xiangyuan tea for 3 months on the glucose and lipid metabolism in a small sample patients with hyperlipidemia (with/without non-alcoholic fatty liver). Jinhua Xiangyuan tea was produced by the new process using Eurotium cristatum. In this study, before-and-after control design was used. The body composition (body weight, BMI, waist hip ratio, percentage of body fat, visceral fat grade), blood biochemical indicators (fasting blood glucose, uric acid, blood lipid), fatty liver, and gut microbiota were examined before and after the test. After drinking Jinhua Xiangyuan tea for 3 months, the body weight, BMI, percentage of body fat, visceral fat grade, serum total cholesterol, low-density lipoprotein cholesterol, and fasting blood glucose of 38 volunteers were significantly reduced (P<0.05). Fatty liver was less severe. Gut microbiota’s diversity and richness were increased. The relative abundance of Phascolarctobacterium, Ruminococcus, Haemophilus and Veillonella were increased, and Dialister and Butyricimonas were decreased. Jinhua Xiangyuan tea could increase the relative abundance of short-chain fatty acid-producing bacteria, increasing short-chain fatty acids, and improving insulin resistance, then improving glucose and lipid metabolism. The results of this study still need to be further confirmed by more rigorous long-term experimental observation.

Key words: Jinhua Xiangyuan tea, glucose and lipid metabolism, gut microbiota, short-chain fatty acids

CLC Number:

SUN Ying, CHEN Xin, YANG Hua, YING Jian, SHAO Danqing, LÜ Xiaohua, XIAO Jie, CHEN Zhixiong, LI Song, QIN Junjie, ZHENG Bin, GAO Jianshe. Clinical Trial on the Effect of Drinking Jinhua Xiangyuan Tea for 3 Months on the Improvement of Glucose and Lipid Metabolism in A Small Sample Hyperlipidemia Population[J]. Journal of Tea Science, 2022, 42(4): 561-576.

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Clinical Trial on the Effect of Drinking Jinhua Xiangyuan Tea for 3 Months on the Improvement of Glucose and Lipid Metabolism in A Small Sample Hyperlipidemia Population

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