Present Status and Development Trends of Research on Tea Polysaccharides

LI Yan; LIN Yongfeng; LIU Wenmei; ZOU Zehua; LIU Guangming; LIU Qingmei

doi:10.13305/j.cnki.jts.2023.04.001

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Journal of Tea Science ›› 2023, Vol. 43 ›› Issue (4) : 447-459. DOI: 10.13305/j.cnki.jts.2023.04.001

Review

Present Status and Development Trends of Research on Tea Polysaccharides

LI Yan¹, LIN Yongfeng¹, LIU Wenmei^2,3,4, ZOU Zehua^2,3,4, LIU Guangming¹, LIU Qingmei^1,*

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Abstract

Tea polysaccharides are important active ingredients in tea. Studying the properties of tea polysaccharides and promoting the development of tea polysaccharides products will benefit both the tea industry and the health industry. In the present paper, literatures related to tea polysaccharides from the Web of Science database over the past decade were visually analyzed. The results show that the overall number of papers related to tea polysaccharides showed an increasing trend from 2013 to 2022. The co-occurrence, emergence and frequency analysis of keywords show that the antioxidant activities of tea polysaccharides are a continuous research hotspot, which may also be one of the main trends in future research. At present, global research on tea polysaccharides mainly focuses on the physicochemical properties including monosaccharide composition, solubility, emulsification and biological activities such as antioxidation, anticancer and antidiabetic. Although tea polysaccharides exhibit a variety of biological activities, the underlying mechanisms are still not well understood. Recent studies have shown that tea polysaccharides can exert probiotic potential by affecting gut microbiota. In addition, the transformation and development of tea polysaccharide-related products are particularly insufficient. In the future, researchers can focus on developing biofilm products, drug delivery vehicles and functional foods using tea polysaccharides. Overall, the present paper summarized the main contents and hot spots in the field of tea polysaccharides, aiming to serve as a reference for researchers in this field as well as for the development of the tea polysaccharide industry.

Key words

antioxidation / gut microbiota / tea polysaccharides / visual analysis

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LI Yan, LIN Yongfeng, LIU Wenmei, ZOU Zehua, LIU Guangming, LIU Qingmei. Present Status and Development Trends of Research on Tea Polysaccharides[J]. Journal of Tea Science. 2023, 43(4): 447-459 https://doi.org/10.13305/j.cnki.jts.2023.04.001

References

[1] 程利增, 朱将雄, 周慧, 等. 茶多糖提取纯化、结构活性及应用研究进展[J]. 中国茶叶, 2021, 43(8): 7-15.
Cheng L Z, Zhu J X, Zhou H, et al.Research progress on the extraction, purification, structures, activities and application of tea polysaccharides[J]. China Tea, 2021, 43(8): 7-15.
[2] 翁昆, 张亚丽. GB/T 30766—2014《茶叶分类》简介[J]. 中国标准导报, 2015(1): 34-35.
Weng K, Zhang Y L.Introduction to GB/T 30766-2014 "Classification of Tea"[J]. China Quality and Standards Review, 2015(1): 34-35.
[3] 欧阳建, 周方, 卢丹敏, 等. 茶多糖调控肥胖作用研究进展[J]. 茶叶科学, 2020, 40(5): 565-575.
Ouyang J, Zhou F, Lu D M, et al.Research progress of tea polysaccharides in regulating obesity[J]. Journal of Tea Science, 2020, 40(5): 565-575.
[4] Chen G, Yuan Q, Saeeduddin M, et al.Recent advances in tea polysaccharides: extraction, purification, physicochemical characterization and bioactivities[J]. Carbohydrate Polymers, 2016, 153: 663-678.
[5] 翁蔚, 李书魁, 张琴梅, 等. 茶多糖的组成与保健功效研究进展[J]. 中华中医药杂志, 2021, 36(12): 7261-7264.
Weng W, Li S K, Zhang Q M, et al.Research progress of composition and health function of tea polysaccharide[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2021, 36(12): 7261-7264.
[6] 李东旭, 陈富桥. 基于CiteSpace文献计量分析的中国茶产业经济研究现状与展望[J]. 华中农业大学学报, 2022, 41(5): 57-67.
Li D X, Chen F Q.Situation and prospect of studies on tea industry in China based on CiteSpace bibliometnic analysis[J]. Journal of Huazhong Agricultural University, 2022, 41(5): 57-67.
[7] 张鑫, 王吉, 胡静荣, 等. 基于Citespace和文献计量分析平台的鱼糜研究可视化分析[J]. 食品科学, 2023, 44(1): 362-370.
Zhang X, Wang J, Hu J R, et al.Visual analysis of surimi research based on Citespace and bibliometric analysis platform[J]. Food Science, 2023, 44(1): 362-370.
[8] Sun Y Q, Wu S M, Gong G Y.Trends of research on polycyclic aromatic hydrocarbons in food: a 20-year perspective from 1997 to 2017[J]. Trends in Food Science & Technology, 2019, 83: 86-98.
[9] Chen S Y, Han R, Liu H T.A bibliometric and visualization analysis of intermittent fasting[J]. Frontiers in Public Health, 2022, 10: 946795. doi: 10.3389/fpubh.2022.946795.
[10] 陈悦, 陈超美, 刘则渊, 等. CiteSpace知识图谱的方法论功能[J]. 科学学研究, 2015, 33(2): 242-253.
Chen Y, Chen C M, Liu Z Y, et al.The methodology function of CiteSpace mapping knowledge domains[J]. Studies in Science of Science, 2015, 33(2): 242-253.
[11] 周钰, 刘庆梅, 张军, 等. 基于Citespace对抗食物过敏研究领域的可视化分析[J]. 中国食品学报, 2021, 21(6): 366-374.
Zhou Y, Liu Q M, Zhang J, et al.Visualization analysis of anti food allergy reasearch based on Citespace[J]. Journal of Chinese Institute of Food Science and Technology, 2021, 21(6): 366-374.
[12] 吴晓秋, 吕娜. 基于关键词共现频率的热点分析方法研究[J]. 情报理论与实践, 2012, 35(8): 115-119.
Wu X Q, Lü N.Research on the hot spot analysis method based on keyword co occurrence frequency[J]. Information Studies: Theory & Application, 2012, 35(8): 115-119.
[13] Li X, Chen S, Li J E, et al.Chemical composition and antioxidant activities of polysaccharides from Yingshan Cloud Mist tea[J]. Oxidative Medicine and Cellular Longevity, 2019, 2019: 1915967. doi: 10.1155/2019/1915967.
[14] Guo L, Guo J C, Zhu W C, et al.Optimized synchronous extraction process of tea polyphenols and polysaccharides from Huaguoshan Yunwu tea and their antioxidant activities[J]. Food and Bioproducts Processing, 2016, 100: 303-310.
[15] 穆军芳, 张丽鑫, 杨光. 基于WOS的国际农业生态学研究热点与前沿探究[J]. 中国生态农业学报(中英文), 2022: 1-12. [2023-05-09]. 基于WOS的国际农业生态学研究热点与前沿探究[J]. 中国生态农业学报(中英文), 2022: 1-12. [2023-05-09]. http://kns.cnki.net/kcms/detail/13.1432.S.20221228.1328.002.html.
Mu J F, Zhang L X, Yang G, et al. A Study on the research hotspots and emerging trends of international agroecology based on WOS [J]. Chinese Journal of Eco-Agriculture, 2022: 1-12. [2023-05-09]. http://kns.cnki.net/kcms/detail/13.1432.S.20221228.1328.002.html.
[16] Qu J L, Huang P, Zhang L, et al.Hepatoprotective effect of plant polysaccharides from natural resources: a review of the mechanisms and structure-activity relationship[J]. International Journal of Biological Macromolecules, 2020, 161: 24-34.
[17] Xu Y L, Wang Y J, He J L, et al.Antibacterial properties of lactoferrin: a bibliometric analysis from 2000 to early 2022[J]. Frontiers in Microbiology, 2022, 13: 947102. doi: 10.3389/fmicb.2022.947102.
[18] Chen G J, Zeng Z Q, Xie M H, et al.Fermentation characteristics and probiotic activity of a purified fraction of polysaccharides from Fuzhuan brick tea[J]. Food Science and Human Wellness, 2022, 11(3): 727-737.
[19] Li H S, Fang Q Y, Nie Q X, et al.Hypoglycemic and hypolipidemic mechanism of tea polysaccharides on type 2 diabetic rats via gut microbiota and metabolism alteration[J]. Journal of Agricultural and Food Chemistry, 2020, 68(37): 10015-10028.
[20] Liu X L, Hu G S, Wang A H, et al.Black tea reduces diet-induced obesity in mice via modulation of gut microbiota and gene expression in host tissues[J]. Nutrients, 2022, 14(8): 1635. doi: 10.3390/nu14081635.
[21] Wang Y L, Zhao Y, Andrae-Marobela K, et al.Tea polysaccharides as food antioxidants: an old woman’s tale?[J]. Food Chemistry, 2013, 138(2/3): 1923-1927.
[22] Lu X S, Zhao Y, Sun Y F, et al.Characterisation of polysaccharides from green tea of Huangshan Maofeng with antioxidant and hepatoprotective effects[J]. Food Chemistry, 2013, 141(4): 3415-3423.
[23] Xu P, Wu J, Zhang Y, et al.Physicochemical characterization of puerh tea polysaccharides and their antioxidant and α-glycosidase inhibition[J]. Journal of Functional Foods, 2014, 6: 545-554.
[24] Chen G J, Xie M H, Wan P, et al.Digestion under saliva, simulated gastric and small intestinal conditions and fermentation in vitro by human intestinal microbiota of polysaccharides from Fuzhuan brick tea[J]. Food Chemistry, 2018, 244: 331-339.
[25] Chen D, Chen G J, Ding Y, et al.Polysaccharides from the flowers of tea (Camellia sinensis L.) modulate gut health and ameliorate cyclophosphamide-induced immunosuppression[J]. Journal of Functional Foods, 2019, 61: 103470. doi: 10.1016/j.jff.2019.103470.
[26] Wu D T, Liu W, Yuan Q, et al.Dynamic variations in physicochemical characteristics of oolong tea polysaccharides during simulated digestion and fecal fermentation in vitro[J]. Food Chemistry: X, 2022, 14: 100288. doi: 10.1016/j.fochx.2022.100288.
[27] Chen H, Huang Y Z, Zhou C C, et al.Effects of ultra-high pressure treatment on structure and bioactivity of polysaccharides from large leaf yellow tea[J]. Food Chemistry, 2022, 387: 132862. doi: 10.1016/j.foodchem.2022.132862.
[28] Jin F, Jia L Y, Tu Y Y.Structural analysis of an acidic polysaccharide isolated from white tea[J]. Food Science and Biotechnology, 2015, 24(5): 1623-1628.
[29] Nie S P, Xie M Y.A review on the isolation and structure of tea polysaccharides and their bioactivities[J]. Food Hydrocolloids, 2011, 25(2): 144-149.
[30] Wang Q, Yang X Y, Zhu C W, et al.Advances in the utilization of tea polysaccharides: preparation, physicochemical properties, and health benefits[J]. Polymers, 2022, 14(14): 2775. doi: 10.3390/polym14142775.
[31] Xu A A, Lai W Y, Chen P, et al.A comprehensive review on polysaccharide conjugates derived from tea leaves: composition, structure, function and application[J]. Trends in Food Science & Technology, 2021, 114: 83-99.
[32] Qin H N, Huang L, Teng J W, et al.Purification, characterization, and bioactivity of Liupao tea polysaccharides before and after fermentation[J]. Food Chemistry, 2021, 353: 129419. doi: 10.1016/j.foodchem.2021.129419.
[33] Xiang G, Sun H P, Chen Y Y, et al.Antioxidant and hypoglycemic activity of tea polysaccharides with different degrees of fermentation[J]. International Journal of Biological Macromolecules, 2023, 228: 224-233.
[34] Sun X Y, Wang J M, Ouyang J, et al.Antioxidant activities and repair effects on oxidatively damaged HK-2 cells of tea polysaccharides with different molecular weights[J]. Oxidative Medicine and Cellular Longevity, 2018, 2018: 5297539. doi: 10.1155/2018/5297539.
[35] Zhang X, Chen H X, Zhang N, et al.Extrusion treatment for improved physicochemical and antioxidant properties of high-molecular weight polysaccharides isolated from coarse tea[J]. Food Research International, 2013, 53(2): 726-731.
[36] Wang Y F, Mao F F, Wei X L.Characterization and antioxidant activities of polysaccharides from leaves, flowers and seeds of green tea[J]. Carbohydrate Polymers, 2012, 88(1): 146-153.
[37] Zhu J X, Yu C, Han Z, et al.Comparative analysis of existence form for selenium and structural characteristics in artificial selenium-enriched and synthetic selenized green tea polysaccharides[J]. International Journal of Biological Macromolecules, 2020, 154: 1408-1418.
[38] Junker F, Michalski K, Guthausen G, et al.Characterization of covalent, feruloylated polysaccharide gels by pulsed field gradient-stimulated echo (PFG-STE)-NMR[J]. Carbohydrate Polymers, 2021, 267: 118232. doi: 10.1016/j.carbpol.2021.118232.
[39] Wang J Y, Liu W, Chen Z Q, et al.Physicochemical characterization of the oolong tea polysaccharides with high molecular weight and their synergistic effects in combination with polyphenols on hepatocellular carcinoma[J]. Biomedicine & Pharmacotherapy, 2017, 90: 160-170.
[40] Chen X Q, Wu X F, Zhang K, et al.Purification, characterization, and emulsification stability of high- and low-molecular-weight fractions of polysaccharide conjugates extracted from green tea[J]. Food Hydrocolloids, 2022, 129: 107667. doi: 10.1016/j.foodhyd.2022.107667.
[41] Li Q, Zhao T T, Shi J L, et al.Physicochemical characterization, emulsifying and antioxidant properties of the polysaccharide conjugates from Chin brick tea (Camellia sinensis)[J]. Food Chemistry, 2022, 395: 133625. doi: 10.1016/j.foodchem.2022.133625.
[42] Li W, Wang K Q, Sun Y, et al.Influences of structures of galactooligosaccharides and fructooligosaccharides on the fermentation in vitro by human intestinal microbiota[J]. Journal of Functional Foods, 2015, 13: 158-168.
[43] Chen H X, Qu Z S, Fu L L, et al.Physicochemical properties and antioxidant capacity of 3 polysaccharides from green tea, oolong tea, and black tea[J]. Journal of Food Science, 2009, 74(6): 469-474.
[44] Hu T, Wu P, Zhan J F, et al.Structure variety and its potential effects on biological activity of tea polysaccharides[J]. Food Science and Human Wellness, 2022, 11(3): 587-597.
[45] Chen H X, Wang Z S, Qu Z S, et al.Physicochemical characterization and antioxidant activity of a polysaccharide isolated from oolong tea[J]. European Food Research and Technology, 2009, 229(4): 629-635.
[46] Yang X H, Huang M J, Qin C Q, et al.Structural characterization and evaluation of the antioxidant activities of polysaccharides extracted from Qingzhuan brick tea[J]. International Journal of Biological Macromolecules, 2017, 101: 768-775.
[47] Chen G J, Wang M J, Xie M H, et al.Evaluation of chemical property, cytotoxicity and antioxidant activity in vitro and in vivo of polysaccharides from Fuzhuan brick teas[J]. International Journal of Biological Macromolecules, 2018, 116: 120-127.
[48] Wang H S, Chen J R, Ren P F, et al.Ultrasound irradiation alters the spatial structure and improves the antioxidant activity of the yellow tea polysaccharide[J]. Ultrasonics Sonochemistry, 2021, 70: 105355. doi: 10.1016/j.ultsonch.2020.105355.
[49] Zheng Q R, Li W F, Zhang H, et al.Optimizing synchronous extraction and antioxidant activity evaluation of polyphenols and polysaccharides from Ya'an Tibetan tea (Camellia sinensis)[J]. Food Science & Nutrition, 2019, 8(1): 489-499.
[50] Xu P, Chen H, Wang Y Q, et al.Oral administration of puerh tea polysaccharides lowers blood glucose levels and enhances antioxidant status in alloxan-induced diabetic mice[J]. Journal of Food Science, 2012, 77(11): 246-252.
[51] Guo R, Zhang J A, Liu X, et al.Pectic polysaccharides from Biluochun tea: a comparative study in macromolecular characteristics, fine structures and radical scavenging activities in vitro[J]. International Journal of Biological Macromolecules, 2022, 195: 598-608.
[52] Tang Y Y, Sheng J F, He X M, et al.Novel antioxidant and hypoglycemic water-soluble polysaccharides from jasmine tea[J]. Foods, 2021, 10(10): 2375. doi: 10.3390/foods10102375.
[53] Fan M H, Zhu J X, Qian Y L, et al.Effect of purity of tea polysaccharides on its antioxidant and hypoglycemic activities[J]. Journal of Food Biochemistry, 2020, 44(8): e13277. doi: 10.1111/jfbc.13277.
[54] Liu L Q, Li H S, Nie S P, et al.Tea polysaccharide prevents colitis-associated carcinogenesis in mice by inhibiting the proliferation and invasion of tumor cells[J]. International Journal of Molecular Sciences, 2018, 19(2): 506. doi: 10.3390/ijms19020506.
[55] Wang Y C, Chen J, Zhang D Z, et al.Tumoricidal effects of a selenium (Se)-polysaccharide from Ziyang green tea on human osteosarcoma U-2 OS cells[J]. Carbohydrate Polymers, 2013, 98(1): 1186-1190.
[56] Wang H J, Shi S S, Bao B, et al.Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect[J]. Carbohydrate Polymers, 2015, 124: 98-108.
[57] Li S Q, Chen H X, Wang J, et al.Involvement of the PI3K/Akt signal pathway in the hypoglycemic effects of tea polysaccharides on diabetic mice[J]. International Journal of Biological Macromolecules, 2015, 81: 967-974.
[58] Chung J O, Yoo S H, Lee Y E, et al.Hypoglycemic potential of whole green tea: water-soluble green tea polysaccharides combined with green tea extract delays digestibility and intestinal glucose transport of rice starch[J]. Food & Function, 2019, 10(2): 746-753.
[59] Zhao Y N, Chen H, Li W T, et al.Selenium-containing tea polysaccharides ameliorate DSS-induced ulcerative colitis via enhancing the intestinal barrier and regulating the gut microbiota[J]. International Journal of Biological Macromolecules, 2022, 209: 356-366.
[60] Kim J, Choi H, Choi D H, et al.Application of green tea catechins, polysaccharides, and flavonol prevent fine dust induced bronchial damage by modulating inflammation and airway cilia[J]. Scientific Reports, 2021, 11(1): 2232. doi: 10.1038/s41598-021-81989-9.
[61] Liu L Q, Nie S P, Shen M Y, et al.Tea polysaccharides inhibit colitis-associated colorectal cancer via interleukin-6/STAT3 pathway[J]. Journal of Agricultural and Food Chemistry, 2018, 66(17): 4384-4393.
[62] Cheng L Z, Chen L, Yang Q Q, et al.Antitumor activity of Se-containing tea polysaccharides against sarcoma 180 and comparison with regular tea polysaccharides and Se-yeast[J]. International Journal of Biological Macromolecules, 2018, 120: 853-858.
[63] 王兆梅, 李琳, 郭祀远, 等. 活性多糖构效关系研究评述[J]. 现代化工, 2002(8): 18-21, 23.
Wang Z M, Li L, Guo S Y, et al.Review on structure-activity relationship of active polysaccharides[J]. Modern Chemical Industry, 2002(8): 18-21, 23.
[64] 杨玉洁, 刘静宜, 谭艳, 等. 多糖降血糖活性构效关系及作用机制研究进展[J]. 食品科学, 2021, 42(23): 355-363.
Yang Y J, Liu J Y, Tan Y, et al.Progress inunderstanding the structure-activity relationship and hypaglycemic mechanism of polysaccharides[J]. Food Science, 2021, 42(23): 355-363.
[65] Wang D Y, Zhao Y, Sun Y F, et al.Protective effects of Ziyang tea polysaccharides on CCl₄-induced oxidative liver damage in mice[J]. Food Chemistry, 2014, 143: 371-378.
[66] 倪德江, 陈玉琼, 宋春和, 等. 乌龙茶多糖对糖尿病大鼠肝肾抗氧化功能及组织形态的影响[J]. 茶叶科学, 2003, 23(1): 11-15.
Ni D J, Chen Y Q, Song C H, et al.Effect of oolong tea polysaccharide on hepatic-nephritic antioxidation and histomorphology in the diabetic rats[J]. Journal of Tea Science, 2003, 23(1): 11-15.
[67] 江和源. 茶叶降血糖活性及对糖尿病的功效与机理[J]. 中国茶叶, 2019, 41(2): 1-6.
Jiang H Y.Hypoglycemic activity of tea and its effect and mechanism on diabetes[J]. China Tea, 2019, 41(2): 1-6.
[68] Monobe M N M, Ema K, Kato F M K, et al. Immunostimulating activity of a crude polysaccharide derived from green tea (Camellia sinensis) extract[J]. Journal of Agricultural and Food Chemistry, 2008, 56(4): 1423-1427.
[69] Yuan C F, Li Z H, Peng F, et al.Combination of selenium-enriched green tea polysaccharides and Huo-ji polysaccharides synergistically enhances antioxidant and immune activity in mice[J]. Journal of the Science of Food and Agriculture, 2015, 95(15): 3211-3217.
[70] Chen X Q, Zhang Z F, Gao Z M, et al.Physicochemical properties and cell-based bioactivity of Pu’erh tea polysaccharide conjugates[J]. International Journal of Biological Macromolecules, 2017, 104: 1294-1301.
[71] Ho Do M, Seo Y S, Park H Y.Polysaccharides: bowel health and gut microbiota[J]. Critical Reviews in Food Science and Nutrition, 2021, 61(7): 1212-1224.
[72] Chen G J, Wang M J, Zeng Z Q, et al.Fuzhuan brick tea polysaccharides serve as a promising candidate for remodeling the gut microbiota from colitis subjects in vitro: fermentation characteristic and anti-inflammatory activity[J]. Food Chemistry, 2022, 391: 133203. doi: 10.1016/j.foodchem.2022.133203.
[73] Li N, Zhou S Y, Yang X B, et al.Applications of natural polysaccharide-based pH-sensitive films in food packaging: current research and future trends[J]. Innovative Food Science & Emerging Technologies, 2022, 82(1): 103200. doi: 10.1016/j.ifset.2022.103200.
[74] Shahidi F, Hossain A.Preservation of aquatic food using edible films and coatings containing essential oils: a review[J]. Critical Reviews in Food Science and Nutrition, 2022, 62(1): 66-105.
[75] Azeredo H M C, Waldron K W. Crosslinking in polysaccharide and protein films and coatings for food contact: a review[J]. Trends in Food Science & Technology, 2016, 52: 109-122.
[76] Shao P, Feng J R, Sun P L, et al.Recent advances in improving stability of food emulsion by plant polysaccharides[J]. Food Research International, 2020, 137: 109376. doi: 10.1016/j.foodres.2020.109376.
[77] Tang Q L, Huang G L.Improving method, properties and application of polysaccharide as emulsifier[J]. Food Chemistry, 2022, 376: 131937. doi: 10.1016/j.foodchem.2021.131937.
[78] Li S Q, Wang X M, Li W W, et al.Preparation and characterization of a novel conformed bipolymer paclitaxel-nanoparticle using tea polysaccharides and zein[J]. Carbohydrate Polymers, 2016, 146: 52-57.
[79] Fan M H, Zhang X, Zhao Y, et al.Mn(II)-mediated self-assembly of tea polysaccharide nanoparticles and their functional role in mice with type 2 diabetes[J]. ACS Applied Materials & Interfaces, 2022, 14(27): 30607-30617.
[80] Albuquerque P B S, De Oliveira W F, Dos Santos Silva P M, et al. Skincare application of medicinal plant polysaccharides: a review[J]. Carbohydrate Polymers, 2022, 277: 118824. doi: 10.1016/j.carbpol.2021.118824.
[81] 李焱, 林泳峰, 刘文美, 等. 食药同源植物多糖调控肠道稳态的研究进展[J]. 食品安全质量检测学报, 2023, 14(2): 25-33.
Li Y, Lin Y F, Liu W M, et al.Research progress on regulating intestinal steady-state of polysaccharides from food-medicine homologous plants[J]. Journal of Food Safety and Quality, 2023, 14(2): 25-33.
[82] Chen X Q, Han Y, Meng H, et al.Characteristics of the emulsion stabilized by polysaccharide conjugates alkali-extracted from green tea residue and its protective effect on catechins[J]. Industrial Crops and Products, 2019, 140: 111611. doi: 10.1016/j.indcrop.2019.111611.
[83] Chen X Q, Zhang Y T, Han Y, et al.Emulsifying properties of polysaccharide conjugates prepared from chin-brick tea[J]. Journal of Agricultural and Food Chemistry, 2019, 67(36): 10165-10173.
[84] Wang C, Fu Y X, Cao Y, et al.Enhancement of lycopene bioaccessibility in tomatoes using excipient emulsions: effect of dark tea polysaccharides[J]. Food Research International, 2023, 163: 112123. doi: 10.1016/j.foodres.2022.112123.
[85] Lin X R, Mu J J, Chen Z Z, et al.Stabilization and functionalization of selenium nanoparticles mediated by green tea and Pu-erh tea polysaccharides[J]. Industrial Crops and Products, 2023, 194: 116312. doi: 10.1016/j.indcrop.2023.116312.
[86] Wu S Y, Li N, Yang C, et al.Synthesis of cationic branched tea polysaccharide derivatives for targeted delivery of siRNA to hepatocytes[J]. International Journal of Biological Macromolecules, 2018, 118: 808-815.