The effect of black tea extracts on extending the lifespan of Caenorhabditis elegans nematode under Oxidative stress was studied by the authors. Results showed the mean lifespan was significantly extended upon the concentration of 50βmg/L black tea extract treatment under oxidative stress. Further studies demonstrated that the significant up-regulation of stress-resistance-related enzyme including superoxide dismutase-3 (SOD-3) by 40.8% and GSH-Px by 340.8%,and its up-regulation of stress-resistance-related proteins, including SKN-1::GFP by 10% and DAF-16::GFP by 18%. These results indicate that black tea extracts can extend the lifespan of Caenorhabditis elegans nematode against oxidative stress.
ZHANG Jian-wei
,
XIONG Zhe
,
GAO Yan
,
PENG Yu-xuan
,
GONG Yu-shun
,
LIU Zhong-hua
. Black Tea Extend the Lifespan of Caenorhabditis elegans Nematode under Oxidative Stress[J]. Journal of Tea Science, 2013
, 33(4)
: 295
-300
.
DOI: 10.13305/j.cnki.jts.2013.04.002
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