Combined Effects of Caffeine and Catechins on the Body Weight and Lipid Metabolism in Mice

YANG Li-cong; ZHENG Guo-dong; WANG Chun-rong; LI Dong-ming

doi:10.13305/j.cnki.jts.2010.05.008

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Journal of Tea Science ›› 2010, Vol. 30 ›› Issue (5) : 374-378. DOI: 10.13305/j.cnki.jts.2010.05.008

Combined Effects of Caffeine and Catechins on the Body Weight and Lipid Metabolism in Mice

YANG Li-cong, ZHENG Guo-dong^*, WANG Chun-rong, LI Dong-ming

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Abstract

To investigate the combined effects of caffeine and catechins on the body weight and lipid metabolism, mice was with on diets containing different concentration of caffeine and catechins for 12 weeks. Organs and intraperitioneal adipose tissues (IPAT) were weighted at the end of this period. Biochemical parameters in the serum and lipid levels in the liver were measured. The body weight gain was significantly reduced by group Ⅳ(0.06% caffeine+0.6% catechins). Weight of IPAT was remarkable reduced in all experiment groups. Serum concentration of NEFA was significantly reduced by group Ⅰ(0.03% caffeine + 0.3% catechins) and group Ⅱ(0.03% caffeine+0.6% catechins). Group Ⅲ(0.06% caffeine+0.3% catechins) and groupⅣ(0.06% caffeine + 0.6% catechins) decreased TC, TG, leptin level in serum. Liver TC and TG levels were reduced by combinations of caffeine and catechins. These results showed the caffeine and catechins combination might reduce lipid levels in the serum and the liver. It causes the suppressive effect on fat accumulation and body weight.

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caffeine / catechins / fat accumulation / lipid metabolism

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YANG Li-cong, ZHENG Guo-dong, WANG Chun-rong, LI Dong-ming. Combined Effects of Caffeine and Catechins on the Body Weight and Lipid Metabolism in Mice[J]. Journal of Tea Science. 2010, 30(5): 374-378 https://doi.org/10.13305/j.cnki.jts.2010.05.008

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