茶多酚与维生素C混合抑制幽门螺杆菌的研究

doi:10.13305/j.cnki.jts.2006.04.012

Abstract

Abstract: The mixture of tea-polyphenol (TP) and vitamin C(VC) with various concentrations were interfused into the liquid medium, then the inhibitive effect of the mixture on Helicobacter Pylori was determined in vitro. The result indicates that the inhibitive effect of the mixed solution of tea-polyphenol and vitamin C is more efficient than that of individuals, separately. The strongest inhibition is 98.23% when the concentration of mixture is TP 1.2βmg/ml, VC 0.08βmg/ml.

Key words: tea-polyphenol, vitamin C, Helicobacter Pylori

CLC Number:

S571.1
R1

XIAO Bo, QU Hui-ge, HUANG Qing-rong, YU Chuan-chuan, ZHAO Bo. Study on the Inhibition of Mixture of Tea-Polyphenol and Vitamin C on Helicobacter Pylori[J]. Journal of Tea Science, 2006, 26(4): 295-298.

References 8

[1]	Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration[J]. Lancet, 1984, 16; 1(8390): 1311~1315.
[2]	金珠, 林三仁, 沈祖尧, 等. 幽门螺杆菌与胃炎活动性关系的病理观察[J]. 北京医科大学学报, 2000, 32(1): 50~52
[3]	Arkkila PE, Seppala K, Farkkila MA, et al. Helicobacter pylori eradication in the healing of atrophic gastritis: a one-year prospective study[J]. Scand J Gastroenterol, 2006, 41(7): 782~790.
[4]	Yang GF, Deng CS, Xiong YY, et al. Expression of nuclear factor-kappa B and target genes in gastric precancerous lesions and adenocarcinoma: association with Helicobactor pylori cagA (+) infection[J]. World J Gastroenterol, 2004, 10(4): 491~496.
[5]	Tombola F, Campello S, De Luca L, et al. Plant polyphenols inhibit VacA, a toxin secreted by the gastric pathogen Helicobacter pylori[J]. FEBS Lett, 2003, 543(1~3): 184~189.
[6]	Tombola F, Campello S, De luca L, et al. Plant polyphenols inhibite VacA, a toxin secreted by the gastric pathogen helicobacter pylori[J]. FEBS Lett, 2003, 543(1~3): 184~189
[7]	Yahiro K, Shirasaka D, Tagashira M, et al. Inhibitory effects of polyphenols on gastric injury by Helicobacter pylori VacA toxin[J]. Helicobacter, 2005, 10(3): 231-239.
[8]	Yee YK, Koo MW.Anti-helicobacter pylori activity of Chinese tea: in vitro study[J]. Aliment Pharmacol Ther, 2000, 14(5): 635~638.

Study on the Inhibition of Mixture of Tea-Polyphenol and Vitamin C on Helicobacter Pylori

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References 8

Related Articles 2

Metrics

Comments

Recommended 10

[1]	WANG Yue-fei, LIANG Shan-zhu, ZHANG Shi-kang, CHEN Hong-bo, ZHU Yue-jin, HUANG Shuang-ru, YANG Xian-qiang. Study on the Toxicology of an Anti-radiation Preparation of Tea-polyphenols [J]. Journal of Tea Science, 2011, 31(5): 405-410.
[2]	SUN Pei-pei, WANG Yue-fei, ZHANG Xing-hai, HU Liu-hong, YANG Xian-qiang. Study on the Toxicology of a Preparation of Tea-polyphenols and American Ginseng [J]. Journal of Tea Science, 2008, 28(6): 450-454.