[1] Zhong Rong, Zhen Zhou, Dao Wei, et al. Effect of tea catechins on regulation of antioxidant enzyme expression in H2O2-induced skeletal muscle cells of goat in vitro[J]. Agric Food Chem, 2011, 59(20): 11338-11343.
[2] Liu ML, Wen JQ, Fan YB.Potential Protection of Green Tea Polyphenols Against 1800 MHz Electromagnetic Radiation-Induced Injury on Rat Cortical Neurons[J]. Neurotoxicity Research, 2011, 20(3): 270-276.
[3] Haza AI, Morales P.Effects of (+)catechin and (-)epicatechin on heterocyclic amines-induced oxidative DNA damage[J]. Journal of Applied Toxicology, 2011, 31(1): 53-62.
[4] Masami S, Achinto S, Hirota F, et al. New cancer treatment strategy using combination of green tea catechins and anticancer drugs[J]. Cancer Science, 2011, 102(2): 317-323.
[5] Maurya PK, Rizvi SI.Protective role of tea catechins on erythrocytes subjected to oxidative stress during human aging[J]. Natural Product Research, 2009, 23(12): 1072-1079.
[6] Rainsa TM, Agarwalb S, Maki KC.Antiobesity effects of green tea catechins: a mechanistic review[J]. The Journal of Nutritional Biochemistry, 2011, 22(10): 1-7.
[7] 李大祥, 鲜殊, 杨卫. 茶叶的神经保护作用研究进展[J]. 茶叶科学, 2011, 31(2): 79-86.
[8] Verschuren L, Wielinga PY, Duyvenvoorde WV, et al. A Dietary Mixture Containing Fish Oil, Resveratrol, Lycopene, Catechins, and Vitamins E and C Reduces Atherosclerosis in Transgenic Mice[J]. Nutr, 2011, 141(5): 863-869.
[9] Sang S, Lambert JD, Yang CS.Bioavailability and stability issues in understanding the cancer preventive effects of tea polyphenols[J]. Journal of the Science of Food and Agriculture, 2006, 86(14): 2256-2265.
[10] Han HK, Amidon GL.Targeted prodrug design to optimize drug delivery[J]. The AAPS Journal, 2000, 2(1): 48-58.
[11] Jarkko R, Hanna K, Tycho H, et al. Prodrugs: design and clinical applications[J]. Nature Reviews Drug Discovery, 2008, 7: 255-270.
[12] 应乐, 张士康, 王岳飞, 等. 茶多酚改性及其抗氧化性能研究进展[J]. 茶叶科学, 2010, 30(增1): 511-515.
[13] Huo C, Dou QP, Chan TH.Synthesis of phosphates and phosphates-acetates hybrids of green tea polyphenol (-)-epigallocatechine-3-gallate (EGCG) and its G ring deoxy analogs as potential anticancer prodrugs[J]. Tetrahedron Letters, 2011, 52(42): 5478-5483.
[14] 伍妍俊, 汪小钢, 宛晓春. 甲基化EGCG 的研究现状及展望[J]. 茶叶科学, 2010, 30(6): 407-413.
[15] 费冬梅. 甲基EGCG的酶法合成研究[D]. 杭州: 中国农业科学院茶叶研究所, 2010.
[16] Kirita M, Honma D, Tanaka Y.Cloning of a Novel O-Methyltransferase from Camellia sinensis and Synthesis of O-Methylated EGCG and Evaluation of their Bioactivity[J]. J Agric Food Chem, 2010, 58(12): 7196-7201.
[17] Zaveri NT.Synthesis of a 3,4,5-Trimethoxybenzoyl Ester Analogue of Epigallocatechin-3-gallate (EGCG): A Potential Route to the Natural Product Green Tea Catechin, EGCG[J]. Org Lett, 2001, 3(6): 843-846.
[18] Waleh N S, Chao WR, Bensari A, et al. Novel D-ring Analog of Epigallocatechin-3-gallate Inhibits Tumor Growth and VEGF expression in breast carcinoma cells[J]. Anticancer research, 2005, 25(1A): 397-402.
[19] 刘晓辉, 江和源, 张建勇, 等. 儿茶素酰基化修饰研究进展[J]. 茶叶科学, 2009, 29(1): 1-8.
[20] 旷英姿, 马全红, 顾宁. 脂溶性茶多酚的制备与表征[J]. 食品科技, 2005 (7): 53-56.
[21] 张健希, 张玉军, 晁燕, 等. 茶多酚脂溶性改性条件的确定及其抗氧化性能的研究[J]. 河北工业大学学报: 自然科学版, 2008, 29(3): 15-19.
[22] 孙东, 陈平. EGCG肉豆蔻酸酯的制备、结构及其抗氧化活性[J]. 温州医学院学报, 2006, 36(3): 225-227.
[23] 陈平, 孙东, 郑小明. EGCG棕榈酸酯的制备、结构及其抗氧化活性[J]. 浙江大学学报: 理学版, 2003, 30(4): 422-425.
[24] 卢聪聪. 茶多酚的化学改性和脂溶性茶多酚分离分析[D]. 上海: 上海交通大学农业与生物学院, 2008.
[25] 王洪新, 聂小华. 油溶性茶多酚——茶多酚脂肪酸酯的研制[J]. 食品科学, 2004, 25(12): 92-96.
[26] 陈理, 孙东. EGCG棕榈酸酯对人卵巢癌HO-8910细胞株的体外抑制活性实验研究[J]. 医学研究杂, 2006, 35(3): 39-40.
[27] 陈平, 孙东. 一种新的儿茶素类食用植物油抗氧化剂[J]. 中国粮油学报, 2003, 18(5): 77-79.
[28] 申雷, 章建浩, 靳国锋. 硬脂酰氯改性对茶多酚抗油脂氧化性能的影响[J]. 食品工业科技, 2012, 33(8): 159-164.
[29] 曾磊, 张玉军, 唐怀建. 脂溶性茶多酚的研制及其抗氧化性能研究[J]. 中国油脂, 2004, 29(11): 54-57.
[30] 沈生荣, 金超芳, 杨贤强. 儿茶素的分子修饰[J]. 茶叶, 1999, 25(2): 76-79.
[31] 刘晓辉, 江和源, 张建勇, 等. 乙酰化EGCG的制备研究[J]. 安徽农业科学, 2009, 37(24): 11360-11363.
[32] 刘屏, 穆丽华, 韩亚亮, 等. 鸡血藤活性化合物儿茶素结构修饰及抗辐射作用研究[J]. 解放军药学报, 2007, 23(5): 321-324.
[33] Mori S, Miyake S, Kobe T.Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: Effect of alkyl chain length[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18(14): 4249-4252.
[34] 江和源. 表没食子儿茶素没食子酸酯全取代乙酰化物的制备方法: 中国, 101519395[P].2009-09-02.
[35] 江和源. 表没食子儿茶素没食子酸酯乙酰化物的制备方法: 中国, 101190910A [P].2008-06-04.
[36] Osanai K, Landis-Piwowar KR, Dou QP, et al. A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer[J]. Bioorganic & Medicinal Chemistry, 2007, 15(15): 5076-5082.
[37] 孙东魁. 儿茶素类蛋白酶体抑制剂的设计合成和初步活性评价[D]. 青岛:中国海洋大学, 2009.
[38] Poaty B, Dumarcay S, Perrin D.New lipophilic catechin derivatives by oxa-Pictet-Spengler reaction[J]. European Food Research and Technology, 2009, 230(1): 111-117.
[39] 钟建华, 陈平, 张广元, 等. 脂溶性茶多酚及其酯化法生产方法: 中国, 99113427.3[P].1999-10-13.
[40] Nakagawa K, Fujii S, Ohgi A, et al. Antioxidative activity of 3-O-Octanoyl-(+)-catechin, a newly synthesized catechin, in vitro[J]. J Health Sci, 2005, 51: 492-496.
[41] 陈平, 孙东. 一种新的儿茶素类食用植物油抗氧化剂[J]. 中国粮油学报, 2003, 18(5): 77-79.
[42] Zhong Y, Shahidi F.Lipophilized epigallocatechin Gallate (EGCG) derivatives as novel antioxidants[J]. J Agric Food Chem, 2011, 59(12): 6526-6533.
[43] Zhong Y, Shahidi F.Lipophilised epigallocatechin gallate (EGCG) derivatives and their antioxidant potential in food and biological systems[J]. J Agric Food Chem, 2012, 131(1): 22-30.
[44] 严梅荣, 王丹丹, 冷媛媛. 脂溶性茶多酚对共轭亚油酸的抗氧化性研究[J]. 中国粮油学报, 2007. 22(1): 83-86.
[45] 陈志华, 李湛静. 粉状脂溶性茶多酚在色拉油中的性能试验[J]. 中国粮油学报, 2007, 25(2): 55-57.
[46] 陈志华, 倪立华, 张守政, 等. 脂溶性茶多酚在大豆色拉油中抗氧活性研究[J]. 中国油脂, 2000, 25(2): 55-57.
[47] 李健. 油溶性茶多酚对油炸花生食品抗氧化的研究[J]. 食品研究与开发, 2010, 31(7): 63-65.
[48] 聂芊, 沈春燕. 分子修饰法制备油溶性茶多酚及其抗氧化性能的研究[J]. 化学世界, 2007(4): 209-211.
[49] 邵卫梁, 杭晓敏, 张蔚, 等.一种脂溶性茶多酚的制备方法: 中国, 101270108[P].2008-09-24.
[50] 张铰铣, 杨贤强. 改性茶多酚在油脂食品中的应用: 中国, 101708062A[P].2010-05-19.
[51] 陈留记, 杨贤强, 张锡林. 乳化剂对茶多酚和脂溶性茶多酚抗亚油酸及其乳化体系氧化作用的影响[J]. 中国粮油学报, 2003, 18(1): 61-64.
[52] Kajiya K, Hojo H, Suzuki M, et al. Relationship between Antibacterial Activity of (+)-Catechin Derivatives and Their Interaction with a Model Membrane[J]. J Agric Food Chem, 2004, 52(6): 1514-1519.
[53] Stapleton PD, Shaha S, Hamilton-Millerb JMT, et al. Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-O-acyl-catechins[J]. International Journal of Antimicrobial Agents, 2004, 24(4): 374-380.
[54] Cushnie TPT, Taylor PW, Nagaoka Y, et al. Investigation of the antibacterial activity of 3-O-octanoyl-(-)-epicatechin[J]. Applied Microbiology, 2008, 105(5): 1461-1469.
[55] Park KD, Cho SJ.Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism[J]. European Journal of Medicinal Chemistry, 2010, 45(3): 1028-1033.
[56] Futamura Y. Method for producing catechin derivative: 日本, 2008-239504[P]. 2008-09-10.
[57] Yasue M, Yamamoto M. Lipopexia inhibitor and food or beverage: 美国, 11/911,711[P/OL]. 2008-01-22. http://www.google.com.hk /patents/US20090312409?dq=methylated+catechins+antiallergic+patent+formulation&ei=h70DT9LPKau6iAfMh9y8Bg.
[58] 张国浩, 吴泽君. 一种含鱼油或多烯鱼油的营养均衡调和油及其生产方法: 中国, 101142947[P].2008-03-19.
[59] 张国浩, 吴泽君. 一种含海狗油的营养均衡调和油及其生产方法: 中国, 101142948[P].2008-03-19.
[60] 张国浩, 吴泽君. 一种含海藻油的营养均衡调和油及其生产方法: 中国, 101124929[P].2008-02-20.
[61] 于新华. 一种富含辅酶Q10的健康食用油: 中国, 1582692[P].2005-02-23.
[62] 余善鸣. 富含维生素E植物调和油的生产方法: 中国, 1600135[P].2005-03-30.
[63] 吴桂荣, 杨静, 杨坤. 硒化3/6平衡食用油: 中国, 101455244[P].2009-06-17.
[64] 陈宗懋. 茶多酚类化合物抗癌的生物化学和分子生物学基础[J]. 茶叶科学, 2003, 23(2): 83-93.
[65] 陈宗懋. 茶叶抗癌研究二十年[J]. 茶叶科学, 2009, 29(3): 173-190.
[66] Bayer J, Gomer A, Demir Y.Effects of green tea polyphenols on murine transplant-reactive T cell immunity[J]. Clinical Immunology, 2004, 110(1): 100-108.
[67] Kang TH, Lee JH, Song CK, et al. Epigallocatechin-3-Gallate enhances CD8+T cell- mediated antitumor immunity induced by DNA vaccination[J]. Cancer Research, 2007, 67: 802-811.
[68] Shimizu K, Shimizu NK, Hakamata W, et al. Preventive Effect of Green Tea Catechins on Experimental Tumor Metastasis in Senescence-Accelerated Mice[J]. Biol Pharm Bull, 2010(33): 117-121.
[69] Chen D, Wan SB, Yang H, et al. EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment[J]. Adv Clin Chem, 2011, 53: 155-177.
[70] Lambert JD, Sang S, Hong J, et al. Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate[J]. Drug Metab Dispos, 2006, 34(12): 2111-2116.
[71] Landis-Piwowar KR, Huo C, Chen D, et al. A novel prodrug of the green tea polyphenol (-)-Epigallocatechin-3-gallate as apotent anticancer agent[J]. Cancer Res, 2007, 67: 4303-4310.
[72] Ahmed K, Wei ZL, Zhao QL, et al. Role of fatty acid chain length on the induction of apoptosis by newly synthesized catechin derivatives[J]. Chemico-Biological Interactions, 2010, 185(3): 182-188.
[73] Matsubara K, Saito A, Tanaka A, et al. Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis[J]. Life Sci, 2007, 80(17): 1578-1585.
[74] Mizushina Y, Saito A, Horikawa K, et al. Acylated catechin derivatives: inhibitors of DNA polymerase and angiogenesis[J]. Front Biosci, 2011(3): 1337-1348.
[75] Sánchez-del-Campo L, Otón F, Tárraga A,#magtechI#et al. Synthesis and biological activity of a 3,4,5-trimethoxybenzoyl ester analogue of epicatechin-3-gallate[J]. Medicinal Chemistry, 2008, 51(7): 2018-2026.
[76] Lozano C, JuliáL, Jiménez A, et al. Electron-transfer capacity of catechin derivatives and influence on the cell cycle and apoptosis in HT29 cells[J]. FEBS Journal, 2006, 273(11): 2475-2486
[77] Songa JM, Parka KD, Lee KH, et al. Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives[J]. Antiviral Research, 2007, 76(2): 178-185.
[78] Shahid F, Zhong Y.Novel antioxidants in food quality preservation and health promotion[J]. European Journal of Lipid Science and Technology. 2010, 112(9): 930-940.
[79] 杨洁, 李润明, 毛芹超. EGCG乙酸酯的HIV融合抑制活性及其作用机制研究[J]. 中国新药杂志, 2010, 19(21): 1967-1972.
[80] 谢子建, 宛晓春, 杨昌军, 等. 表儿茶素没食子酸酯及其衍生物在治疗或预防心肌梗塞等缺血性心脏病中的用途: 中国, 101984965A[P].2011-03-16.
[81] Kurita I, Maeda-Yamamoto M, Tachibana H, et al. Antihypertensive effect of Benifuuki tea containing O-methylated EGCG[J]. Agric Food Chem, 2010, 58(3): 1903-1908.
[82] Chao JF, Lau WKW, Huie MJ, et al. A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine[J]. Neuroscience Letters, 2010, 469(3): 360-364.
[83] Fujiki H, Suganuma M, Imai K, et al. Green tea: Cancer preventive beverage and/or drug[J]. Cancer Lett, 2002, 188(1/2): 9-13.
[84] Katherine MW Pisters, Robert A Newman, Brenda Coldman, et al. Phase I trial of oral green tea extract in adult patients with solid tumors[J]. Clinical Oncology, 2001, 19(6): 1830-1838.
[85] Jatoi A, Ellison N, Burch PA, et al. A Phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma[J]. Cancer, 2003, 97(6): 1442-1446.
[86] Moyers SB, H MP, Kumar NB. Green Tea Polyphenols and Cancer Chemoprevention: Multiple Mechanisms and Endpoints for Phase II Trials[J]. Nutrition Reviews, 2004, 62(5): 204-211.
[87] Shanafelt TD, Call TG, Zent CS, et al. Phase I Trial of Daily Oral Polyphenon E in Patients With Asymptomatic Rai Stage 0 to II Chronic Lymphocytic Leukemia[J]. Clinical Oncology, 2009, 27(23): 3808-3814.
[88] 贾立红. 脂溶性茶多酚静脉纳米乳剂的制备[D]. 长春: 吉林大学, 2006.
[89] 浙江大学. 脂溶性茶多酚的开发[DB]. 国家科技成果数据库: 知网版, 2008-01-01.
[90] Driessen WE. Non-lonic surfactant solubilized high catechin content emulsion: 美国, 12/932,265[P].2011-02-22.
[91] 鲍士宝. 茶多酚纳米粒复合明胶膜的研究[D]. 无锡: 江南大学, 2009.
[92] 马全红, 郝晓帧, 旷英姿. 表面活性剂对茶多酚脂质体的制备及透皮性能的影响[J]. 东南大学学报: 自然科学版, 2007, 37(1): 132-135.
[93] 邓泽元, 余迎利, 微胶囊油溶性茶多酚生产技术[J]. 精细与专用化学品, 2004, 12(16): 8-11, 15.
[94] Peresa I, Rocha S, Gomes J, et al. Preservation of catechin antioxidant properties loaded in carbohydrate nanoparticles[J]. Carbohydrate Polymers, 2011, 86(1): 147-153.
[95] Dube A, Nicolazzo JA, Larson I.Chitosan nanoparticles enhance the plasma exposure of (-)-epigallocatechin gallate in mice through an enhancement in intestinal stability[J]. European Journal of Pharmaceutical Sciences, 2011, 44(3): 422-426.
[96] Onoue S, Ochi M, Yamada S.Development of (-)-epigallocatechin-3-gallate (EGCG)-loaded enteric microparticles with intestinal mucoadhesive property[J]. International Journal of Pharmaceutics, 2011, 410(1-2): 111-113.
[97] Li JL, Zu YG, Zhao XH, et al. Preparation, Characterization, and In Vitro Evaluation of EGCG-Loaded Chitosan Nanoparticles[J]. Advanced Materials Research, 2011(282/283): 539-544.
[98] Yamamoto M, Kirita M, Sami M. Gene encoding methylated catechin synthase: 欧洲, 20050806065[P/OL]. 2007-08-01. http://www.freepatentsonline.com/EP1813674.html.
[99] Saijo R.Isolation and chemical structures of two new catechins from fresh tea leaf[J]. Agricultural and Biological Chemistry, 1982, 46(7): 1969-1970.
[100] Yamamoto M, Nagai H. Anti-allergic agent and beverage/food, preparation for external application or cosmetic comprising the agent: 美国, 12/160,554[P].2007-07-19.
[101] 裘炳毅. 化妆品化学与工艺技术大全: 上、下册[M]. 北京: 中国轻工业出版社, 1997.
[102] Yamamoto M, Kirita M, Honma D, et al. Novel methylated catechin and composion containing the same: 欧洲, 20080703535[P/OL]. 2009-11-18. http://www.freepatentsonline.com/EP2119712.html.
[103] 刘玮, 张怀亮. 皮肤科学和化妆品功效评价[M]. 北京: 化学工业出版社, 2005.
[104] 徐向群. 茶叶提取物在化妆品上的应用[J]. 中国茶叶, 1993, 15(3): 31-32.
[105] 杨贤强. 茶多酚化学[M]. 上海: 上海科学技术出版社, 2003: 126, 201-267.
[106] 陆建良, 梁月荣, 金晶, 等. 一种抗UV-B辐射损伤的防护剂: 中国, 1876064[P].2006-12-13.
[107] Hsu SD. Modified Green Tea Polyphenol Formulations: 美国, 12/063139 [P].2008-07-24.
[108] 隋丽华, 郭珉. 茶多酚皮肤药理学的研究进展[J]. 医药导报, 2003, 22(11): 807-809.
[109] Mahmood T, Akhtar N, Khan BA, et al. Outcomes of 3% green tea emulsion on skin sebum production in male volunteers[J]. Bosnian Journal of Basic Medical Sciences, 2010, 10(3): 260-264.