多酚自组装抗菌生物材料的构建及其应用进展

doi:10.13305/j.cnki.jts.2024.01.004

Abstract

Abstract: Bacterial infection, a leading cause of global mortality, can result in various diseases. While antibiotics are the primary treatment for infections, their excessive and irrational use has led to the emergence of a variety of bacterial drug resistance, posing a serious threat to human health. Plant polyphenols have natural antibacterial properties, but the instability of the phenolic hydroxyl structure limits their bioavailability. To solve this problem, researchers have explored the self-assembly of polyphenols with other substances to construct new nano-biomaterials. These biomaterials not only enhance the stability and bioavailability of polyphenols but also exhibit synergistic antibacterial activity, showing a great promise in the field of antibacterial applications. This review examined the construction strategies and antibacterial properties of different types of polyphenol self-assembled biomaterials developed in recent years, including polyphenol-metal, polyphenol-hydrogel, polyphenol-chitosan, polyphenol-protein and polyphenol-liposome. Furthermore, the challenges and future prospects of the novel polyphenol self-assembling biomaterials in the field of antibacterial application were discussed.

Key words: polyphenols, self-assembly, nanomaterials, antibacterial applications

CLC Number:

XU Wei, YU Rongxin, ZHANG Xiangchun, ZHANG Yiwen, CHEN Hongping, TIAN Baoming, ZHENG Qinqin, WU Yuanyuan, XIA Chen, WEI Bing. Construction of Polyphenol Self-assembly Antibacterial Biomaterials and Progress in Their Applications[J]. Journal of Tea Science, 2024, 44(1): 1-15.

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Construction of Polyphenol Self-assembly Antibacterial Biomaterials and Progress in Their Applications

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