云南普洱茶特征成分的功能与毒理学评价

doi:10.13305/j.cnki.jts.2007.03.011

Journal of Tea Science ›› 2007, Vol. 27 ›› Issue (3): 201-210.doi: 10.13305/j.cnki.jts.2007.03.011

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Evaluation on the Function and Toxicity of Extraction of Characteristic Components in Yunnan pu-erh Tea

GONG Jia-shun¹, CHEN Wen-ping², ZHOU Hong-jie^{3, *}, DONG Zhao-jun⁴, ZHANG Yi-fang⁵

1. Faculty of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China;
2. College of Food Science, Southwest University, Chongqing 400716, China;
3. Department of Tea Science, Yunnan Agricultural University, Kunming 650201, China;
4. Department of Military Toxicology , Third Military Medical University, Chongqing 400038, China;
5. College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China

Received:2007-03-04 Revised:2007-06-03 Online:2007-09-25 Published:2019-09-11

Abstract

Abstract: ：The anti-fatigue, reduced cholesterol function, acute toxicity and the mutagenicity of extraction of characteristic components in Yunnan pu-erh tea were studied using mouse as experimental animals. It had significant function of anti-fatigue and reduced cholesterol for mouse, its effects was better than that of water extracts of pu-erh tea. The oral acute toxicity in mouse,Ames test,micronucleus test in bone narrow and chromosome abnormality test of characteristic components extraction in Yunnan pu-erh tea were also carried out．The oral LD₅₀ value of this extraction in mouse was more than 10.0βg/kg．The number of relevant strain colonies had no remarkable increase in the Ames test with and without S₉ mixture, and the relationship of dose-response was also not found. The micronucleus rates and chromosome abnormality rates at all range of doses had no significant difference compared with the control group. At the dose of 500~5β000βμg/ml, the characteristic components extraction could not cause the increase of mutagenic rate of CHL (Chinese Hamster Lung Fibroblast, CHL) cells. It suggested that the extraction of characteristic components in Yunnan pu-erh tea has no mutagenicity for mouse．

Key words: pu-erh tea, characteristic components, anti-fatigue, reduced cholesterol, acute toxicity, mutagenicity

CLC Number:

S571.1
Q523

GONG Jia-shun, CHEN Wen-ping, ZHOU Hong-jie, DONG Zhao-jun, ZHANG Yi-fang. Evaluation on the Function and Toxicity of Extraction of Characteristic Components in Yunnan pu-erh Tea[J]. Journal of Tea Science, 2007, 27(3): 201-210.

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Evaluation on the Function and Toxicity of Extraction of Characteristic Components in Yunnan pu-erh Tea

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